02412
乙醇胺 溶液
suitable for peptide synthesis, ~74% (T), ~70% in methanol
别名:
2-氨基乙醇
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关于此项目
经验公式（希尔记法）:
C2H7NO
化学文摘社编号:
分子量:
61.08
PubChem Substance ID:
UNSPSC Code:
12352209
Beilstein/REAXYS Number:
3535200
MDL number:
SMILES string
NCCO
InChI
1S/C2H7NO/c3-1-2-4/h4H,1-3H2
InChI key
HZAXFHJVJLSVMW-UHFFFAOYSA-N
assay
~74% (T)
concentration
~70% in methanol
refractive index
n20/D 1.422
solubility
heptane: soluble less than 0.1%, carbon tetrachloride: soluble 0.2%, benzene: soluble 1.4%, diethyl ether: soluble 2.1%, H2O: miscible, acetone: miscible, alcohol: miscible, chloroform: miscible, hexane: insoluble, methanol: miscible
application(s)
peptide synthesis
Application
Ethanolamine solution was used as a medium supplement utilized in proliferation assay. The product was used for preparing the transferrin conjugate which in turn was used for studying whether adriamycin are cytotoxic without intercalating nuclear DNA. Further, ethanolamine along with [9,10(n)-3H]oleate synthesizes [3H]OEA (Oleoylethanolamide).
Biochem/physiol Actions
Ethanolamine is a compound derived from cell membranes and is utilized as a source of carbon and/or nitrogen. It can regulate the expression of genes that encodes components in interkingdom signaling to activate virulence gene expression in Escherichia coli O157:H7 (EHEC). It also serves as a STAT-3-dependent cardioprotective agent.
Preparation Note
Ethanolamine solution is miscible in methanol, acetone, water, chloroform and glycerine. The product is immiscible in solvent hexane, fixed oils as well as ether. Additionally, the product is soluble in 1.4% benzene, 2.1% ether, 0.2% carbon tetrachloride and less than 0.1% heptane at 25 degrees c.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 1 - STOT SE 3
target_organs
Eyes,Central nervous system, Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
89.6 °F - closed cup
flash_point_c
32 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
K Barabas et al.
The Journal of biological chemistry, 267(13), 9437-9442 (1992-05-05)
Studies of the biological chemistry of most anticancer drugs have revealed their cytotoxicity is expressed after the drugs have entered cells. It is thought that anthracycline antitumor drugs exert their cytotoxicity by entering cells, diffusing into nuclei, and inhibiting topoisomerase
Melissa M Kendall et al.
mBio, 3(3), doi:10-doi:10 (2012-05-17)
Bacterial pathogens must be able to both recognize suitable niches within the host for colonization and successfully compete with commensal flora for nutrients in order to establish infection. Ethanolamine (EA) is a major component of mammalian and bacterial membranes and
Mie Julin Nielsen et al.
Journal of lipid research, 45(6), 1027-1029 (2004-04-03)
Oleoylethanolamide (OEA) may be an endogenous regulator of food intake, and intraperitoneal injection of this compound decreases food intake in 24 h-starved rats. It is generally believed that this kind of lipid amide is rapidly catabolized in the gastrointestinal tract
Roisin F Kelly et al.
Basic research in cardiology, 105(6), 763-770 (2010-10-13)
Ethanolamine is a biogenic amine found naturally in the body as part of membrane lipids and as a metabolite of the cardioprotective substances, sphingosine-1-phosphate (S1P) and anandamide. In the brain, ethanolamine, formed from the breakdown of anandamide protects against ischaemic
Purification and characterization of a newly identified growth factor specific for epithelial cells.
J S Rubin et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(3), 802-806 (1989-02-01)
A growth factor specific for epithelial cells was identified in conditioned medium of a human embryonic lung fibroblast cell line. The factor, provisionally termed keratinocyte growth factor (KGF) because of its predominant activity on this cell type, was purified to
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