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Merck
CN

02412

Sigma-Aldrich

乙醇胺 溶液

suitable for peptide synthesis, ~74% (T), ~70% in methanol

别名:

2-氨基乙醇

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关于此项目

经验公式(希尔记法):
C2H7NO
化学文摘社编号:
分子量:
61.08
Beilstein:
3535200
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
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方案

~74% (T)

浓度

~70% in methanol

折射率

n20/D 1.422

溶解性

heptane: soluble less than 0.1%
carbon tetrachloride: soluble 0.2%
benzene: soluble 1.4%
diethyl ether: soluble 2.1%
H2O: miscible
acetone: miscible
alcohol: miscible
chloroform: miscible
hexane: insoluble
methanol: miscible

应用

peptide synthesis

SMILES字符串

NCCO

InChI

1S/C2H7NO/c3-1-2-4/h4H,1-3H2

InChI key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

应用

Ethanolamine solution was used as a medium supplement utilized in proliferation assay. The product was used for preparing the transferrin conjugate which in turn was used for studying whether adriamycin are cytotoxic without intercalating nuclear DNA. Further, ethanolamine along with [9,10(n)-3H]oleate synthesizes [3H]OEA (Oleoylethanolamide).

生化/生理作用

Ethanolamine is a compound derived from cell membranes and is utilized as a source of carbon and/or nitrogen. It can regulate the expression of genes that encodes components in interkingdom signaling to activate virulence gene expression in Escherichia coli O157:H7 (EHEC). It also serves as a STAT-3-dependent cardioprotective agent.

制备说明

Ethanolamine solution is miscible in methanol, acetone, water, chloroform and glycerine. The product is immiscible in solvent hexane, fixed oils as well as ether. Additionally, the product is soluble in 1.4% benzene, 2.1% ether, 0.2% carbon tetrachloride and less than 0.1% heptane at 25 degrees c.

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 1 - STOT SE 3

靶器官

Eyes,Central nervous system, Respiratory system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

89.6 °F - closed cup

闪点(°C)

32 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Melissa M Kendall et al.
mBio, 3(3), doi:10-doi:10 (2012-05-17)
Bacterial pathogens must be able to both recognize suitable niches within the host for colonization and successfully compete with commensal flora for nutrients in order to establish infection. Ethanolamine (EA) is a major component of mammalian and bacterial membranes and
Mie Julin Nielsen et al.
Journal of lipid research, 45(6), 1027-1029 (2004-04-03)
Oleoylethanolamide (OEA) may be an endogenous regulator of food intake, and intraperitoneal injection of this compound decreases food intake in 24 h-starved rats. It is generally believed that this kind of lipid amide is rapidly catabolized in the gastrointestinal tract
K Barabas et al.
The Journal of biological chemistry, 267(13), 9437-9442 (1992-05-05)
Studies of the biological chemistry of most anticancer drugs have revealed their cytotoxicity is expressed after the drugs have entered cells. It is thought that anthracycline antitumor drugs exert their cytotoxicity by entering cells, diffusing into nuclei, and inhibiting topoisomerase
Roisin F Kelly et al.
Basic research in cardiology, 105(6), 763-770 (2010-10-13)
Ethanolamine is a biogenic amine found naturally in the body as part of membrane lipids and as a metabolite of the cardioprotective substances, sphingosine-1-phosphate (S1P) and anandamide. In the brain, ethanolamine, formed from the breakdown of anandamide protects against ischaemic
J S Rubin et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(3), 802-806 (1989-02-01)
A growth factor specific for epithelial cells was identified in conditioned medium of a human embryonic lung fibroblast cell line. The factor, provisionally termed keratinocyte growth factor (KGF) because of its predominant activity on this cell type, was purified to

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