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Merck
CN

03768

Sigma-Aldrich

′L-β-Homoproline′ hydrochloride

≥98.0% (TLC)

别名:

(S)-2-(2-Pyrrolidinyl)acetic acid hydrochloride

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关于此项目

经验公式(希尔记法):
C6H11NO2 · HCl
化学文摘社编号:
分子量:
165.62
Beilstein:
471672
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26
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质量水平

方案

≥98.0% (TLC)

表单

powder

颜色

white to light brown

应用

peptide synthesis

SMILES字符串

Cl.OC(=O)C[C@@H]1CCCN1

InChI

1S/C6H11NO2.ClH/c8-6(9)4-5-2-1-3-7-5;/h5,7H,1-4H2,(H,8,9);1H/t5-;/m0./s1

InChI key

VQDACVOAOJQTPR-JEDNCBNOSA-N

应用

L-β-homoproline is a non-coded α-imino acid used in organic peptide synthesis.

生化/生理作用

L-β-Homoproline is a β amino acid useful in peptide and protein conformation studies.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sándor Góbi et al.
Physical chemistry chemical physics : PCCP, 12(41), 13603-13615 (2010-09-21)
In order to test the pseudo-γ-turn forming capability of β-homo-proline (β(3)-HPro) 2-[(2S)-1-acetylpyrrolidin-2-yl]-N-methylacetamide (Ac-β(3)-HPro-NHMe) was synthesized and its potential energy landscape was investigated by infrared (IR) and vibrational circular dichroism (VCD) spectroscopy combined with density functional calculations. Based upon a comparison
Dariusz Sobolewski et al.
Journal of peptide science : an official publication of the European Peptide Society, 15(3), 161-165 (2008-11-28)
Using SPPS techniques, six new analogues of AVP and some of its agonists were synthesised. The peptides were designed by substitution of Phe at position 3 of AVP, [Mpa(1)] AVP (dAVP) and [Mpa(1),Val(4),D-Arg(8)]VP (dVDAVP) with L- or D-Pip, a non-coded
New bradykinin B(2) receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties.
Sleszynska M, Kwiatkowska A, et al.
Acta Biochimica Polonica, 56, 6410648-6410648 (2009)

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