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经验公式（希尔记法）:
C15H14O6 · xH2O
化学文摘社编号:
分子量:
290.27 (anhydrous basis)
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-825-1
Beilstein/REAXYS Number:
92762
MDL number:
InChI key
OFUMQWOJBVNKLR-NQQJLSKUSA-N
InChI
1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
SMILES string
[H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
grade
primary reference standard
assay
>90.0%
form
powder
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
application(s)
food and beverages
storage temp.
−20°C
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General description
Catechin hydrate, a flavononol, belongs to the class of flavonoids. It is present in abundance in Siberian larch (Larix sibirica) and in silymarin extract of milk thistle seeds. Its potent chemopreventive action by virtue of the regulation of genes through the ARE-dependent pathway has been widely investigated. It also shows potential antioxidant activity against ovarian cancer cell growth, cellular melanogenesis, human breast cancer, etc.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Exact content by quantitative NMR can be found on the certificate.
Application
Catechin hydrate may be used as a reference standard for the determination of the analyte in walnut leaves by high-performance liquid chromatography (HPLC).
Biochem/physiol Actions
多酚抗氧化剂。用于中药。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
HPLC determination of phenolic acids, flavonoids and juglone in walnut leaves
Nour V, et al.
Journal of Chromatographic Science, 51(9) (2013)
T Miyazawa
BioFactors (Oxford, England), 13(1-4), 55-59 (2001-03-10)
Green tea is consumed as a popular beverage in Japan and throughout the world. During the past decade, epidemiological studies have shown that tea catechin intake is associated with lower risk of cardiovascular disease. In vitro biochemical studies have reported
Elena Roura et al.
Clinical chemistry, 52(4), 749-752 (2006-02-14)
Plant polyphenols have been studied largely because of the possibility that they might underlie the protective effects afforded by fruit and vegetable intake against cancer and other chronic diseases. Measurement of polyphenol content excreted in urine as an indicator of
R Hursel et al.
Obesity reviews : an official journal of the International Association for the Study of Obesity, 12(7), e573-e581 (2011-03-04)
Different outcomes of the effect of catechin-caffeine mixtures and caffeine-only supplementation on energy expenditure and fat oxidation have been reported in short-term studies. Therefore, a meta-analysis was conducted to elucidate whether catechin-caffeine mixtures and caffeine-only supplementation indeed increase thermogenesis and
Silvia Mandel et al.
Free radical biology & medicine, 37(3), 304-317 (2004-06-30)
Neurodegeneration in Parkinson's, Alzheimer's, and other neurodegenerative diseases seems to be multifactorial, in that a complex set of toxic reactions including inflammation, glutamatergic neurotoxicity, increases in iron and nitric oxide, depletion of endogenous antioxidants, reduced expression of trophic factors, dysfunction
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