03936
倍他米松21-戊酸酯
pharmaceutical impurity standard
别名:
Betamethasone Related Compound A (USP), Betamethasone impurity E (PhEur)
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关于此项目
经验公式（希尔记法）:
C27H37FO6
化学文摘社编号:
分子量:
476.58
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
analytical standard
Quality Level
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
impurities
≤10.0% related substances, ≤5.0% solvents, ≤5.0% water
application(s)
pharmaceutical (small molecule)
storage temp.
2-8°C
SMILES string
CCCCC(=O)OCC(=O)[C@@]1(O)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
InChI
1S/C27H37FO6/c1-5-6-7-23(32)34-15-22(31)27(33)16(2)12-20-19-9-8-17-13-18(29)10-11-24(17,3)26(19,28)21(30)14-25(20,27)4/h10-11,13,16,19-21,30,33H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1
InChI key
FEROCCAEIIKMJT-SUYDQAKGSA-N
General description
Betamethasone 21-valerate is an active pharmaceutical ingredient present in various topical pharmaceutical creams.
Application
Betamethasone 21-valerate may be used as a reference standard in the determination of betamethasone 21-valerate in counterfeit drugs using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC/ESI‐MS). It may be used as a pharmaceutical impurity standard in the quantification of impurities of betamethasone 21-valerate in topical pharmaceutical creams using high-performance liquid chromatography (HPLC).
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