InChI
1S/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
SMILES string
[Li+].[Li+].[O-]C([O-])=O
InChI key
XGZVUEUWXADBQD-UHFFFAOYSA-L
impurities
lithium carbonate
density
1.00 g/mL at 20 °C
suitability
suitable for microscopy
Gene Information
human ... GSK3A(2931), GSK3B(2932), IMPA1(3612)
法规信息
新产品
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Tom Bschor et al.
Journal of clinical psychopharmacology, 33(1), 38-44 (2013-01-02)
Studies of the 1970s and 1980s showed lithium monotherapy to be an effective treatment of acute unipolar major depressive disorder (MDD) and hence as a potential alternative to monoaminergic antidepressants.The objective was to conduct the first comparison of a lithium
Janusz Rybakowski et al.
Psychiatria polska, 46(4), 627-636 (2012-12-12)
In 1963 it was first demonstrated that long-term lithium administration exerts a "mood-stabilising" effect, preventing recurrences of mania and depression in bipolar affective disorder. Despite the introduction of many other drugs having mood-stabilising effect, lithium still remains the first choice
A simple question answered: adding moderate-dosage lithium does not help patients with bipolar disorder.
Boadie W Dunlop et al.
The American journal of psychiatry, 170(1), 9-11 (2013-01-05)
Andrew A Nierenberg et al.
The American journal of psychiatry, 170(1), 102-110 (2013-01-05)
Lithium salts, once the mainstay of therapy for bipolar disorder, have tolerability issues at a higher dosage that often limit adherence. The authors investigated the comparative effectiveness of more tolerable dosages of lithium as part of optimized personalized treatment (OPT).
A Halboos et al.
Deutsche medizinische Wochenschrift (1946), 137(49), 2583-2585 (2012-11-29)
A 69-year-old man came to the emergency unit because of vertigo and presyncope. A bipolar disorder - known since an age of 15 years - has been treated with 2 × 450 mg lithium and 100 mg perazine per day for several
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