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Merck
CN

06069

夹竹桃苷

analytical standard

别名:

5β,20(22)-Cardenolide-3β,14,16β-triol-3-([2,6-dideoxy-3-O-methyl-α-L-arabinohexopyranosyl]oxy) 16-acetate, Corrigen, Foliandrin, Folinerin, Neriol, Neriolin, Neriostene

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关于此项目

经验公式（希尔记法）:
C32H48O9
化学文摘社编号:
465-16-7
分子量:
576.72
NACRES:
NA.24
UNSPSC Code:
85151701
EC Number:
207-361-5

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产品名称

夹竹桃苷, analytical standard

InChI key

JLPDBLFIVFSOCC-XYXFTTADSA-N

InChI

1S/C32H48O9/c1-17-29(35)24(37-5)14-27(39-17)41-21-8-10-30(3)20(13-21)6-7-23-22(30)9-11-31(4)28(19-12-26(34)38-16-19)25(40-18(2)33)15-32(23,31)36/h12,17,20-25,27-29,35-36H,6-11,13-16H2,1-5H3/t17-,20+,21-,22-,23+,24-,25-,27-,28-,29-,30-,31+,32-/m0/s1

SMILES string

CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@H]2CC[C@@]3(C)C(CCC4C3CC[C@]5(C)[C@H]([C@H](C[C@]45O)OC(C)=O)C6=CC(=O)OC6)C2

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤5.0% water

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

100

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Biochem/physiol Actions

Cardiac glycoside, inhibits Na(+)/K(+) ATPase; potent carcinostatic cardiac glycoside.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCJ5094
BCCH9040
BCCH6807
BCCH4729
BCCH0743

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Amitava Dasgupta et al.
Therapeutic drug monitoring, 28(2), 282-285 (2006-04-22)
Despite known toxicity of oleander, this product is used in herbal preparations. Oleander interferes with various digoxin immunoassays. It is possible that a person taking digoxin also may take oleander-containing herbal products, and digoxin immunoassays interfering with oleander cannot be
Brian J Poindexter et al.
Journal of toxicology and environmental health. Part A, 70(6), 568-574 (2007-03-17)
Oleanders are common, hardy shrubs that grow throughout the southern United States. They contain cardiotonic steroids formed from cardenolides and bufadienolides, making the plant poisonous to both animals and humans. Aliquots of both commercially available oleander and fresh oleander extracts
Cecilia Gechtman et al.
Journal of analytical toxicology, 30(9), 683-686 (2006-12-02)
A female, aged 43 and a male, aged 66, experienced gastrointestinal and cardiovascular symptoms after a meal including snail stew. Twelve hours after the ingestion, they presented with nausea, vomiting, diarrhea, and cardiovascular symptoms typical of acute toxic digoxin ingestion
Sunil K Manna et al.
Journal of cellular physiology, 207(1), 195-207 (2005-12-07)
Considering the potential role of interleukin-8 (IL-8) in inflammation, angiogenesis, tumorogenesis, and metastasis, and the involvement of different cell types especially neutrophils and macrophages in those processes, the regulation of IL-8-mediated biological responses is important. In this report we provide
Elizabeth R Tor et al.
Journal of agricultural and food chemistry, 53(11), 4322-4325 (2005-05-26)
A rapid LC-MS/MS method, using a triple-quadrupole/linear ion trap mass spectrometer, was developed for the quantitative determination of oleandrin in serum, urine, and tissue samples. Oleandrin, the major cardiac glycoside of oleander (Nerium oleander L.), was extracted from serum and
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