06922
蜡酸
analytical standard
别名:
二十六酸, 虫蜡酸
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关于此项目
线性分子式:
CH3(CH2)24COOH
化学文摘社编号:
分子量:
396.69
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-040-2
Beilstein/REAXYS Number:
1799681
MDL number:
InChI key
XMHIUKTWLZUKEX-UHFFFAOYSA-N
InChI
1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28)
SMILES string
CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O
grade
analytical standard
assay
≥95.0% (GC)
form
powder or crystals
shelf life
limited shelf life, expiry date on the label
format
neat
functional group
carboxylic acid
storage temp.
2-8°C
Quality Level
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General description
Hexacosanoic acid is classified under the very long chain fatty acids (VLCFAs) group of biologically important compounds.
Application
Hexacosanoic acid may be used as a reference standard for the determination of hexacosanoic acid
- in human serum and plasma samples for the screening of peroxisomal disorders by gas chromatography-mass spectrometry (GC-MS) operating under selected-ion monitoring (SIM) mode
- in biological samples by GC-MS
- in microalgal lipids by solid-phase extraction (SPE) followed by GC-MS analysis
- as a naphthoxyethyl derivative by high performance liquid chromatography (HPLC) coupled with fluorometric detection
Analysis Note
LC-MS: identity conformes
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Separation of triacylglycerols and free fatty acids in microalgal lipids by solid-phase extraction for separate fatty acid profiling analysis by gas chromatography.
Paik MJ, et al.
Journal of Chromatography A, 1216(31), 5917-5923 (2009)
Gas chromatography/mass spectrometry analysis of very long chain fatty acids, docosahexaenoic acid, phytanic acid and plasmalogen for the screening of peroxisomal disorders.
Takemoto Y, et al.
Brain & Development, 25(7), 481-487 (2003)
A fluorimetric liquid chromatography for highly sensitive analysis of very long chain fatty acids as naphthoxyethyl derivatives.
Lu CY, et al.
Chromatographia, 51(5-6), 315-321 (2000)
High sensitivity quantitative lipidomics analysis of fatty acids in biological samples by gas chromatography-mass spectrometry.
Quehenberger O, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1811(11), 648-656 (2011)
Nicol Kruska et al.
Biochimica et biophysica acta, 1852(5), 925-936 (2015-01-15)
X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder resulting from defective ABCD1 transport protein. ABCD1 mediates peroxisomal uptake of free very-long-chain fatty acids (VLCFA) as well as their CoA-esters. Consequently, VLCFA accumulate in patients' plasma and tissues, which is considered
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