06957
(−)-Chicoric acid
analytical standard
别名:
(2R,3R)-2,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy}butanedioic acid, 2,3-Di-trans-caffeoyltartaric acid
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关于此项目
经验公式（希尔记法）:
C22H18O12
化学文摘社编号:
分子量:
474.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI key
YDDGKXBLOXEEMN-IABMMNSOSA-N
SMILES string
OC(=O)[C@H](OC(=O)\C=C\c1ccc(O)c(O)c1)[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O
InChI
1S/C22H18O12/c23-13-5-1-11(9-15(13)25)3-7-17(27)33-19(21(29)30)20(22(31)32)34-18(28)8-4-12-2-6-14(24)16(26)10-12/h1-10,19-20,23-26H,(H,29,30)(H,31,32)/b7-3+,8-4+/t19-,20-/m1/s1
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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General description
Chicoric acid, a caffeic acid derivative, is found in a variety of plant species, including basil, chicory, dandelion, etc. It is a polyphenol organic compound that is reported to have antioxidant, anti-inflammatory, antiviral and immunostimulating properties. Various studies also suggest the antidiabetic potential of chicoric acid.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
This compound is commonly found in plants of the genus: echinacea
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chicoric acid found in basil (Ocimum basilicum L.) leaves
Lee J and Scagel CF
Food Chemistry, 115(2), 650-656 (2009)
Chung Mu Park et al.
European journal of pharmacology, 660(2-3), 454-459 (2011-04-26)
Synergistic anti-inflammatory effects of luteolin and chicoric acid, two abundant constituents of the common dandelion (Taraxacum officinale Weber), were investigated in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. Co-treatment with luteolin and chicoric acid synergistically reduced cellular concentrations of nitric oxide
Albert Ribas-Agustí et al.
Phytochemical analysis : PCA, 22(6), 555-563 (2011-03-25)
Lettuce is a widely consumed vegetable and a good source of phenolic compounds. Several factors (genetic, agronomical and environmental) can influence the lettuce composition; their effects are not completely defined and more studies are needed on this topic. To develop
Kiranjeet Kour et al.
Pharmacology, biochemistry, and behavior, 99(3), 342-348 (2011-05-31)
The present study was taken up to see the effect of chicoric acid (CA) on behavioral and biochemical alterations induced by chronic restraint stress in experimental Swiss albino mice. CA at 1mg/kg dose level exhibited considerable antidepressant activity as shown
Peter Silhár et al.
Journal of the American Chemical Society, 132(9), 2868-2869 (2010-02-18)
A new mechanistic class of BoNT/A zinc metalloprotease inhibitors, from Echinacea, exemplified by the natural product d-chicoric acid (I1) is disclosed. A detailed evaluation of chicoric acid's mechanism of inhibition reveals that the inhibitor binds to an exosite, displays noncompetitive
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