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经验公式(希尔记法):
C22H18O12
化学文摘社编号:
分子量:
474.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
产品名称
(−)-Chicoric acid, analytical standard
InChI key
YDDGKXBLOXEEMN-IABMMNSOSA-N
SMILES string
OC(=O)[C@H](OC(=O)\C=C\c1ccc(O)c(O)c1)[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O
InChI
1S/C22H18O12/c23-13-5-1-11(9-15(13)25)3-7-17(27)33-19(21(29)30)20(22(31)32)34-18(28)8-4-12-2-6-14(24)16(26)10-12/h1-10,19-20,23-26H,(H,29,30)(H,31,32)/b7-3+,8-4+/t19-,20-/m1/s1
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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General description
Chicoric acid, a caffeic acid derivative, is found in a variety of plant species, including basil, chicory, dandelion, etc. It is a polyphenol organic compound that is reported to have antioxidant, anti-inflammatory, antiviral and immunostimulating properties. Various studies also suggest the antidiabetic potential of chicoric acid.
Other Notes
This compound is commonly found in plants of the genus: echinacea
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Paula N Brown et al.
Journal of AOAC International, 94(5), 1400-1410 (2011-12-15)
A method previously validated to determine caftaric acid, chlorogenic acid, cynarin, echinacoside, and cichoric acid in echinacea raw materials has been successfully applied to dry extract and liquid tincture products in response to North American consumer needs. Single-laboratory validation was
Rui Liu et al.
Biotechnology progress, 27(6), 1672-1679 (2011-08-19)
Recently, cichoric acid production from hairy roots of Echinacea purpurea was significantly improved by ultrasound stimulation in an airlift bioreactor. In this article, the possible mechanism on ultrasound-intensified hairy root culture of E. purpurea in the bioreactor was elucidated with
Kiranjeet Kour et al.
Pharmacology, biochemistry, and behavior, 99(3), 342-348 (2011-05-31)
The present study was taken up to see the effect of chicoric acid (CA) on behavioral and biochemical alterations induced by chronic restraint stress in experimental Swiss albino mice. CA at 1mg/kg dose level exhibited considerable antidepressant activity as shown
Peter Silhár et al.
Journal of the American Chemical Society, 132(9), 2868-2869 (2010-02-18)
A new mechanistic class of BoNT/A zinc metalloprotease inhibitors, from Echinacea, exemplified by the natural product d-chicoric acid (I1) is disclosed. A detailed evaluation of chicoric acid's mechanism of inhibition reveals that the inhibitor binds to an exosite, displays noncompetitive
Chung Mu Park et al.
European journal of pharmacology, 660(2-3), 454-459 (2011-04-26)
Synergistic anti-inflammatory effects of luteolin and chicoric acid, two abundant constituents of the common dandelion (Taraxacum officinale Weber), were investigated in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. Co-treatment with luteolin and chicoric acid synergistically reduced cellular concentrations of nitric oxide
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