07297
丁苄唑啉 盐酸盐
analytical standard
别名:
2-(4-叔-丁基-2,6-二甲基苄基)-2-咪唑啉 盐酸盐
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关于此项目
经验公式（希尔记法）:
C16H24N2 · HCl
化学文摘社编号:
分子量:
280.84
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
214-936-4
MDL number:
InChI key
YGWFCQYETHJKNX-UHFFFAOYSA-N
InChI
1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
SMILES string
CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤1.0% water
application(s)
forensics and toxicology
veterinary
format
neat
Quality Level
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General description
Xylometazoline hydrochloride is a derivative of imidazole, and a representative of the class of α1 agonists. It is commonly used in nasal decongestants, which works on the principle of constricting the blood vessels in the mucous membranes.
Application
Xylometazoline hydrochloride may be used as a reference standard in determining the xylometazoline hydrochloride content in samples of nasal drops using high performance liquid chromatography (HPLC).
Biochem/physiol Actions
α-肾上腺素能受体激动剂；咪唑啉结合位点配体。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Decongestant activity of a new formulation of xylometazoline nasal spray: a double-blind, randomized versus placebo and reference drugs controlled, dose-effect study.
FC and GM
Drugs Under Experimental and Clinical Research, 28(1), 27-35 (2002)
High-performance liquid chromatographic method for the assay of dexamethasone and xylometazoline in nasal drops containing methyl p-hydroxybenzoate.
Milojevic Z, et al.
Journal of Chromatography A, 949(1-2), 79-82 (2002)
Pharmaceutical Chemistry E-Book (2011)
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