07372
Coelenterazine
别名:
8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one
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关于此项目
经验公式（希尔记法）:
C26H21N3O3
化学文摘社编号:
分子量:
423.46
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
fluorescence
λex 400 nm; λem 514 nm in 0.1 M phosphate pH 7.0
suitability
corresponds for UV spectrum
storage temp.
−20°C
SMILES string
Oc1ccc(CC2=NC3=C(Cc4ccccc4)NC(=CN3C2=O)c5ccc(O)cc5)cc1
InChI
1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
InChI key
YHIPILPTUVMWQT-UHFFFAOYSA-N
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Assay of mitochondrial calcium flux; calcium fosters the decomposition to CO2 and coelenteramide with bioluminescence.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Elena V Eremeeva et al.
FEBS letters, 586(23), 4173-4179 (2012-10-24)
Many proteins require a non-covalently bound ligand to be functional. How ligand binding affects protein conformation is often unknown. Here we address thermal unfolding of the free and ligand-bound forms of photoprotein obelin. Fluorescence and far-UV circular dichroism (CD) data
M L N Dubuisson et al.
Drug development and industrial pharmacy, 31(9), 827-849 (2005-11-25)
Coelenterazine and derivatives were initially considered in the scientific community for their (bio)luminescent properties. Now, another interest of such hetero-bicycles has been pointed out by the discovery of remarkable antioxidative properties, and an unique mode of action as a "cascade":
Takahiro Suzuki et al.
Analytical biochemistry, 415(2), 182-189 (2011-04-12)
We have developed a method of video rate bioluminescence imaging to investigate protein secretion from a single mammalian cell and analyzed the localization, secretory frequency, and quantification of secreted protein. By detecting the luminescence signals from the Gaussia luciferase (GLase)
Satoshi Inouye et al.
Protein expression and purification, 88(1), 150-156 (2013-01-01)
The cold-induced expression system in Escherichia coli is useful and we have applied this system to prepare the coelenterazine-utilizing luciferases including Renilla luciferase (RLase), a red-shifted variant of Renilla luciferase (RLase-547), the catalytic domain of Oplophorus luciferase (19kOLase) and Gaussia
M Sarah S Bovenberg et al.
Analytical chemistry, 84(2), 1189-1192 (2011-12-14)
Secreted Gaussia luciferase (Gluc) has been shown to be a useful tool for ex vivo monitoring of in vivo biological processes. The Gluc level in the blood was used to detect tumor growth, metastasis and response to therapy, gene transfer
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 151572-25G | 04061838739278 |
| 151572-100G | 04061838346148 |
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