07549
1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐
≥97.0% (TLC)
别名:
PyBOP®
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关于此项目
线性分子式:
C18H28N6OP · PF6
化学文摘社编号:
分子量:
520.39
PubChem Substance ID:
UNSPSC Code:
41116105
Beilstein/REAXYS Number:
3584612
MDL number:
assay
≥97.0% (TLC)
mp
~150 °C, 154-156 °C (dec.) (lit.)
SMILES string
F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5
InChI
1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChI key
VIAFLMPQBHAMLI-UHFFFAOYSA-N
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Application
BOP 偶联剂类似物，不产生致癌副产物 HMPA。
Legal Information
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany
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Fazel Shabanpoor et al.
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The potential for therapeutic application of splice-switching oligonucleotides (SSOs) to modulate pre-mRNA splicing is increasingly evident in a number of diseases. However, the primary drawback of this approach is poor cell and in vivo oligonucleotide uptake efficacy. Biological activities can
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The rigid geometry and tunable chemistry of D,L-cyclic peptides makes them an intriguing building-block for the rational design of nano- and microscale hierarchically structured materials. Herein, we utilize a combination of electron microscopy, nanomechanical characterization including depth sensing-based bending experiments
Liz O'Donovan et al.
Nucleic acid therapeutics, 25(1), 1-10 (2014-11-21)
We describe two new methods of parallel chemical synthesis of libraries of peptide conjugates of phosphorodiamidate morpholino oligonucleotide (PMO) cargoes on a scale suitable for cell screening prior to in vivo analysis for therapeutic development. The methods represent an extension
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 194115-100G | 04061832418803 |
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