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Merck
CN

07969

Sigma-Aldrich

O-(2-氨基乙基)聚乙二醇 3,000

Mp 3,000

别名:

氨基聚乙二醇

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关于此项目

线性分子式:
NH2(CH2CH2O)nH
CAS Number:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.22
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分子量

Mp 3,000

质量水平

反应适用性

reagent type: cross-linking reagent

Ω端

hydroxyl

α端

amine

SMILES字符串

[H]OCCN

InChI

1S/C2H7NO/c3-1-2-4/h4H,1-3H2

InChI key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

一般描述

O -(2-氨基乙基)聚乙二醇是可用于缀合和交联反应的杂双官能聚乙二醇(羟基-PEG-胺)。

应用

O-(2-氨基乙基)聚乙二醇已用于合成PEG-聚(D,L-丙交酯-co-乙交酯)(PEG-PLGA)共轭物,用于合成基于PLGA的 纳米粒子。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alan O Burts et al.
Photochemistry and photobiology, 90(2), 380-385 (2013-10-15)
New strategies for the synthesis of multifunctional particles that respond to external stimuli and release biologically relevant agents will enable the discovery of new formulations for drug delivery. In this article, we combine two powerful methods: brush-first ring-opening metathesis polymerization
Molly A Sowers et al.
Nature communications, 5, 5460-5460 (2014-11-19)
Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics. Herein, we report the development of a new class of branched-bottlebrush polymer dual-modality organic radical contrast agents--ORCAFluors--for combined magnetic resonance and near-infrared fluorescence imaging in vivo. These nitroxide radical-based nanostructures
Jeremiah A Johnson et al.
Journal of the American Chemical Society, 133(3), 559-566 (2010-12-15)
The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we demonstrate the facile synthesis of a new class of clickable, branched nanostructures, polyethylene glycol (PEG)-branch-azide
Alan O Burts et al.
Macromolecular rapid communications, 35(2), 168-173 (2013-11-23)
This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(lactic acid) (PLA) MM is synthesized via a combination of atom
Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil.
El-Hammadi
International Journal of Pharmaceutics, 516(1-2), 61-70 (2017)

商品

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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