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Merck
CN

07969

O-(2-氨基乙基)聚乙二醇 3,000

Mp 3,000

别名:

氨基聚乙二醇

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关于此项目

线性分子式:
NH2(CH2CH2O)nH
化学文摘社编号:
32130-27-1
UNSPSC Code:
12162002
PubChem Substance ID:
24846131
NACRES:
NA.22
MDL number:
MFCD00286223

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产品名称

O-(2-氨基乙基)聚乙二醇 3,000, Mp 3,000

InChI key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

InChI

1S/C2H7NO/c3-1-2-4/h4H,1-3H2

SMILES string

[H]OCCN

mol wt

Mp 3,000

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

α-end

amine

Quality Level

100

相关类别

Application

O-（2-氨基乙基）聚乙二醇已用于合成PEG-聚（D,L-丙交酯-co-乙交酯）（PEG-PLGA）共轭物，用于合成基于PLGA的 纳米粒子。

General description

O -（2-氨基乙基）聚乙二醇是可用于缀合和交联反应的杂双官能聚乙二醇（羟基-PEG-胺）。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCG6970
BCBW1386
BCBW0934
BCBV4499
BCBV5012

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Angela X Gao et al.
ACS macro letters, 3(9), 854-857 (2014-09-23)
A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when employed in conjunction with a poly(ethylene
Jeremiah A Johnson et al.
Macromolecules, 43(24), 10326-10335 (2011-05-03)
Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; these materials were prepared by graft-through ROMP of drug-loaded polyethylene-glycol (PEG)
Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil.
El-Hammadi
International Journal of Pharmaceutics, 516(1-2), 61-70 (2017)
Alan O Burts et al.
Macromolecular rapid communications, 35(2), 168-173 (2013-11-23)
This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(lactic acid) (PLA) MM is synthesized via a combination of atom
Jeremiah A Johnson et al.
Journal of the American Chemical Society, 133(3), 559-566 (2010-12-15)
The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we demonstrate the facile synthesis of a new class of clickable, branched nanostructures, polyethylene glycol (PEG)-branch-azide
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