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Merck
CN

07969

O-(2-氨基乙基)聚乙二醇 3,000

Mp 3,000

别名:

氨基聚乙二醇

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关于此项目

线性分子式:
NH2(CH2CH2O)nH
化学文摘社编号:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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产品名称

O-(2-氨基乙基)聚乙二醇 3,000, Mp 3,000

InChI key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

InChI

1S/C2H7NO/c3-1-2-4/h4H,1-3H2

SMILES string

[H]OCCN

mol wt

Mp 3,000

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

α-end

amine

Quality Level

Application

O-(2-氨基乙基)聚乙二醇已用于合成PEG-聚(D,L-丙交酯-co-乙交酯)(PEG-PLGA)共轭物,用于合成基于PLGA的 纳米粒子。

General description

O -(2-氨基乙基)聚乙二醇是可用于缀合和交联反应的杂双官能聚乙二醇(羟基-PEG-胺)。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil.
El-Hammadi
International Journal of Pharmaceutics, 516(1-2), 61-70 (2017)
Alan O Burts et al.
Macromolecular rapid communications, 35(2), 168-173 (2013-11-23)
This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(lactic acid) (PLA) MM is synthesized via a combination of atom
Angela X Gao et al.
ACS macro letters, 3(9), 854-857 (2014-09-23)
A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when employed in conjunction with a poly(ethylene
Jeremiah A Johnson et al.
Macromolecules, 43(24), 10326-10335 (2011-05-03)
Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; these materials were prepared by graft-through ROMP of drug-loaded polyethylene-glycol (PEG)
Molly A Sowers et al.
Nature communications, 5, 5460-5460 (2014-11-19)
Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics. Herein, we report the development of a new class of branched-bottlebrush polymer dual-modality organic radical contrast agents--ORCAFluors--for combined magnetic resonance and near-infrared fluorescence imaging in vivo. These nitroxide radical-based nanostructures

商品

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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