08485
甲氧基乙酸
analytical standard
别名:
NSC 7300
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关于此项目
线性分子式:
CH3OCH2COOH
化学文摘社编号:
分子量:
90.08
UNSPSC Code:
12352200
NACRES:
NA.24
PubChem Substance ID:
EC Number:
210-894-6
Beilstein/REAXYS Number:
635800
MDL number:
grade
analytical standard
Quality Level
assay
≥96.5% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.417 (lit.)
bp
202-204 °C (lit.)
mp
7-9 °C (lit.)
density
1.174 g/mL at 25 °C (lit.)
application(s)
environmental
format
neat
SMILES string
COCC(O)=O
InChI
1S/C3H6O3/c1-6-2-3(4)5/h2H2,1H3,(H,4,5)
InChI key
RMIODHQZRUFFFF-UHFFFAOYSA-N
General description
Methoxyacetic acid, a major metabolite of ethylene glycol monomethyl ether, belongs to the class of glycol ethers, which find wide use in industrial applications involving epoxy resin coatings, paints, lacquers, etc.
Application
Methoxyacetic acid may be used as an analytical standard for the determination of the analyte in biological samples by various chromatography techniques.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
237.2 °F - closed cup
flash_point_c
114 °C - closed cup
E J Moss et al.
Toxicology and applied pharmacology, 79(3), 480-489 (1985-07-01)
The role of metabolism in 2-methoxyethanol (ME)-induced testicular toxicity has been investigated with Sprague-Dawley rats. Following administration of [14C]ME (250 mg/kg, ip) to a group of animals, there was evidence of testicular damage, identified as depletion of the spermatocyte population.
A W Smallwood et al.
Environmental health perspectives, 57, 249-253 (1984-08-01)
Glycol ethers are known to produce embryotoxic and teratogenic effects in a variety of animal species. In addition, testicular edema and tubular atrophy have been reported. The health effects of this class of compounds are not known in humans, despite
D Groeseneken et al.
British journal of industrial medicine, 43(1), 62-65 (1986-01-01)
Methoxyacetic acid (MAA) and ethoxyacetic acid (EAA), the major metabolites of, respectively, ethylene glycol monomethyl ether and ethylene glycol monoethyl ether and their acetates, are determined by gas chromatography after extraction from urine and methylation using 2-furoic acid (2-FA) as
Kozo Yokota et al.
International archives of occupational and environmental health, 78(8), 650-654 (2005-07-08)
To investigate whether methoxyacetic acid (MAA) is the metabolite of ethylene glycol dimethyl ether (EGdiME) in humans and whether its metabolite in urine can be used as a biomarker for exposure to EGdiME. Workers occupationally exposed to EGdiME, as well
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Y0000372 | 04061833803257 |
| PHR3038-100MG | 04065266899634 |
| M28006-100G | 04061834046110 |
| 1411016-3X50MG | 04061833845790 |
| M28006-25G | 04061837013416 |
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