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Merck
CN

08930

2-氨基-5-硝基苯酚

technical, 90-95% (NT)

别名:

2-羟基-4-硝基苯胺

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关于此项目

线性分子式:
H2NC6H3(NO2)OH
化学文摘社编号:
分子量:
154.12
EC Number:
204-503-8
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
972974
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grade

technical

assay

90-95% (NT)

mp

198-202 °C (dec.) (lit.)

SMILES string

Nc1ccc(cc1O)[N+]([O-])=O

InChI

1S/C6H6N2O3/c7-5-2-1-4(8(10)11)3-6(5)9/h1-3,9H,7H2

InChI key

DOPJTDJKZNWLRB-UHFFFAOYSA-N

Application

用于以下反应的反应物:
  • 重氮化和偶联反应
  • 生物学和药理活性分子的制备


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2-Amino-5-nitrophenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 177-184 (1993-01-01)
F Chen et al.
Cancer letters, 126(1), 67-74 (1998-05-01)
Two hair dye components, carcinogenic 4-nitro-2-aminophenol and 5-nitro-2-aminophenol, induced Cu(II)-dependent DNA cleavage frequently at thymine and guanine residues in DNA fragments obtained from the c-Ha-ras-1 protooncogene. When the p53 tumor suppressor gene was used, 4-nitro-2-aminophenol caused Cu(II)-dependent piperidine-labile sites at
Weixia Zhu et al.
Se pu = Chinese journal of chromatography, 30(9), 870-875 (2013-01-05)
An analytical method was developed for the simultaneous determination of 11 aminophenols in direct and oxidized hair dyes by high performance liquid chromatography (HPLC). The samples were extracted with methanol using sodium bisulfite for anti-oxidation. The purification was carried out



全球贸易项目编号

货号GTIN
135186-1L04061838730534
135186-250ML04061838730541