等级
technical
方案
≥90% (NT)
杂质
≤3% water
mp
85-92 °C
SMILES字符串
Nc1nccs1
InChI
1S/C3H4N2S/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)
InChI key
RAIPHJJURHTUIC-UHFFFAOYSA-N
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Ian Bruce et al.
Bioorganic & medicinal chemistry letters, 22(17), 5445-5450 (2012-08-07)
Using a parallel synthesis approach to target a non-conserved region of the PI3K catalytic domain a pan-PI3K inhibitor 1 was elaborated to provide alpha, delta and gamma isoform selective Class I PI3K inhibitors 21, 24, 26 and 27. The compounds
Zhili Liu et al.
Bioorganic & medicinal chemistry, 16(14), 6675-6681 (2008-06-20)
A series of apomorphine ((-)-1, APO)-derived analogues ((+/-)-3, (-)-4-(-)-6) were designed and synthesized by hybridizing APO with a privileged 2-aminothiazole functionality which was lent from the orally available anti-parkinsonian drug, pramipexole (2). Among these hybridized compounds, catecholic aporphine (-)-6 shows
Irene Lagoja et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 43(5), 386-392 (2011-06-15)
A novel series of 2-aminothiazoles with strong protection in an Alzheimer's disease (AD) model comprising tau-induced neuronal toxicity is disclosed. These derivatives can be synthesized in one-pot and a small SAR of the substitution within these series afforded several compounds
Sina Ghaemmaghami et al.
Journal of virology, 84(7), 3408-3412 (2009-12-25)
Prion diseases are fatal, untreatable neurodegenerative diseases caused by the accumulation of the misfolded, infectious isoform of the prion protein (PrP), termed PrP(Sc). In an effort to identify novel inhibitors of prion formation, we utilized a high-throughput enzyme-linked immunosorbent assay
Breland Smith et al.
Bioorganic & medicinal chemistry letters, 22(10), 3567-3570 (2012-04-21)
This Letter presents the synthesis and biological evaluation of a collection of 2-aminothiazoles as a novel class of compounds with the capability to reduce the production of PGE(2) in HCA-7 human adenocarcinoma cells. A total of 36 analogs were synthesized
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持