09480
2-氨基噻唑
technical, ≥90% (NT)
别名:
2-噻唑胺
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关于此项目
经验公式（希尔记法）:
C3H4N2S
化学文摘社编号:
分子量:
100.14
EC Number:
202-511-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
105738
MDL number:
InChI key
RAIPHJJURHTUIC-UHFFFAOYSA-N
InChI
1S/C3H4N2S/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)
SMILES string
Nc1nccs1
grade
technical
assay
≥90% (NT)
impurities
≤3% water
mp
85-92 °C
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
R Romagnoli et al.
Current medicinal chemistry, 17(30), 3488-3502 (2010-08-27)
Adenosine is an important autocoid, exerting its physiological effects on the human body by activation of four different G-protein-coupled-receptors (GPCRs) classified as A(1), A(2A), A(2B), and A(3). These receptors are coupled to secondary messenger systems including adenylate cyclase, inositol phosphate
Jiazhong Li et al.
Analytica chimica acta, 631(1), 29-39 (2008-12-03)
In this study, the quantitative structure-activity relationship (QSAR) of a series of 2-aminothiazole based Lck inhibitors was investigated. The key structural features responsible for the inhibition activities were discussed in detail. A population of 100 rigorously validated linear QSAR models
Qingping Zeng et al.
Bioorganic & medicinal chemistry letters, 20(5), 1652-1656 (2010-02-09)
A series of 2-aminothiadiazole of inhibitors of AKT1 is described. SAR relationships are discussed, along with selectivity for protein kinase A (PKA) and cyclin-dependent kinase 2 (CDK2). Moderate selectivity observed in several compounds for AKT1 versus PKA is rationalized by
Samantha Leone et al.
Bioorganic & medicinal chemistry, 16(10), 5695-5703 (2008-04-15)
REST/NRSF is a multifunctional transcription factor that represses or silences many neuron-specific genes in both neural and non-neural cells by recruitment to its cognate RE1/NRSE regulatory sites. An increase in RE1/NRSE genomic binding is found in Huntington's disease (HD), resulting
Mari Kuramoto et al.
Organic & biomolecular chemistry, 6(15), 2772-2781 (2008-07-18)
A series of 2-(2-aminothiazol-4-yl)benzo[b]furan and 3-(2-aminothiazol-4-yl)benzo[b]furan derivatives were prepared, and their leukotriene B(4) inhibitory activity and growth inhibitory activity in cancer cell lines were evaluated. Several compounds showed strong inhibition of calcium mobilization in CHO cells overexpressing human BLT(1) and
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