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关于此项目
经验公式(希尔记法):
C7H8F3N3O4S2
化学文摘社编号:
分子量:
319.28
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-506-8
Beilstein/REAXYS Number:
1164542
MDL number:
InChI key
KRVABEGPNKGLOT-UHFFFAOYSA-N
InChI
1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17)
SMILES string
Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F
grade
technical
assay
≥96% (HPLC)
ign. residue
≤2%
mp
241-246 °C
Quality Level
Gene Information
human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
O Brørs et al.
Acta pharmacologica et toxicologica, 51(4), 273-277 (1982-10-01)
The inhibitory effect of hydroflumethiazide (HFT) and its metabolite, 2,4-disulfamyl-5-trifluoromethylaniline (DTA) on cyclic AMP phosphodiesterase and the binding of HFT and DTA to carbonic anhydrase was studied in vitro. Significant inhibition of rat kidney low-Km cyclic AMP phosphodiesterase was observed
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