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关于此项目
经验公式(希尔记法):
C16H19N3O5S
化学文摘社编号:
分子量:
365.40
EC Number:
248-003-8
UNSPSC Code:
51101500
MDL number:
Beilstein/REAXYS Number:
7507120
InChI
1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1
InChI key
LSQZJLSUYDQPKJ-NJBDSQKTSA-N
SMILES string
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O
assay
≥97.0% (dried material, NT)
impurities
~15% water
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
General description
Chemical structure: β-lactam
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
László Szabó et al.
Free radical research, 50(1), 26-38 (2015-10-03)
Penicillins, as bactericidal antibiotics, have been widely used to treat infections for several decades. Their structure contains both aromatic and thioether moieties susceptible to free radical oxidation. The (•)OH induced oxidation mechanism of amoxicillin was investigated by pulse radiolysis techniques
Thao Thi Nguyen et al.
Scientific reports, 9(1), 9349-9349 (2019-06-30)
This study investigates the photocatalytic degradation of amoxicillin (AMO) by simulated solar irradiation using WO3 as a catalyst. A three-factor-three-level Box-Behnken design (BBD) consisting of 30 experimental runs is employed with three independent variables: initial AMO concentration, catalyst dosage, and
Allison R Bechard et al.
Behavioral neuroscience, 133(2), 247-254 (2019-02-05)
Research using the cocaine self-administration and reinstatement animal model of relapse finds that the beta-lactam antibiotic, ceftriaxone, attenuates cocaine-primed reinstatement of cocaine seeking and upregulates two proteins that regulate glutamate release and reuptake (xCT and GLT-1, respectively) in the nucleus
Jakob Menz et al.
Environmental science & technology, 52(11), 6555-6564 (2018-04-10)
There are growing concerns that antibiotic pollution impacts environmental microbiota and facilitates the propagation of antibiotic resistance. However, the prediction or analytical determination of bioavailable concentrations of antibiotics in soil is still subject to great uncertainty. Biological assays are increasingly
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