方案
~95% (TLC)
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
InChI
1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
InChI key
SKVLYVHULOWXTD-UHFFFAOYSA-N
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一般描述
Chemical structure: sulfonamide
Succinylsulfathiazole in the nutrition of the rat.
L D WRIGHT et al.
The American journal of the medical sciences, 212(3), 312-314 (1946-09-01)
A G Fogg et al.
Journal of clinical pharmacy and therapeutics, 17(2), 107-109 (1992-04-01)
Ethylenediaminetetraacetic acid (EDTA) was shown to be effective in stabilizing pharmaceutical compounds, which contain acetamido groups, from degradation by light, e.g. paracetamol. Its addition is particularly effective in stabilizing such compounds from the action of ascorbic acid in the light
Tyrosine oxidation by livers from rats with a sulfasuxidine-induced pteroylglutamic acid deficiency.
G RODNEY et al.
The Journal of biological chemistry, 168(1), 395-395 (1947-04-01)
Intraperitoneal administration of succinylsulfathiazole and phthalylsulfathiazole; their use in the prophylaxis and treatment of peritonitis.
J P YOUNG et al.
Archives of surgery (Chicago, Ill. : 1920), 53, 182-189 (1946-08-01)
R L Walzem et al.
The Journal of nutrition, 118(11), 1343-1348 (1988-11-01)
Thiamin absorption and excretion were assessed in rats with severe folate deficiency (FD) by determining the fate of oral 3H-labeled and intravenous 14C-labeled thiamin over a 6-h test period. Thiamin status was evaluated in these same rats by measuring transketolase
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