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Merck
CN

11320

阿托品

≥95.0% (NT)

别名:

(8-甲基-8-氮杂双环[3.2.1]辛-3-基) endo-(+/-)-α-(羟甲基)苯乙酸酯, 莨菪碱, 龙葵碱

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关于此项目

经验公式(希尔记法):
C17H23NO3
化学文摘社编号:
分子量:
289.37
EC Number:
200-104-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
91260
MDL number:
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assay

≥95.0% (NT)

ign. residue

≤0.05%

mp

115-118 °C

SMILES string

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

InChI key

RKUNBYITZUJHSG-SPUOUPEWSA-N

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Biochem/physiol Actions

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Incidence, pathophysiology, and treatment of complications during dobutamine-atropine stress echocardiography.
Marcel L Geleijnse et al.
Circulation, 121(15), 1756-1767 (2010-04-21)
D Poldermans et al.
European heart journal, 18 Suppl D, D86-D96 (1997-06-01)
Cardiac events in the peri-operative phase and late after non-cardiac vascular surgery are a major cause of morbidity and mortality. Numerous tests and diagnostic strategies--usually consisting of a combination of analysis of clinical risk factors and additional non-exercise dependent stress
Peter Jones et al.
Archives of disease in childhood, 97(2), 139-144 (2011-05-31)
Bradycardia occurs during the intubation of some critically ill children as a result of vagal stimulation due to hypoxia and/or laryngeal stimulation; such 'stable' bradycardia is accompanied by selective vasoconstriction. Some induction drugs also induce bradycardia which may be accompanied
Kevan A C Martin et al.
Nature communications, 5, 5252-5252 (2014-10-25)
The axons of pyramidal neurons in the superficial layers of the neocortex of higher mammals form lateral networks of discrete clusters of synaptic boutons. In primary visual cortex the clusters are reported to link domains that share the same orientation
Michela Faggioni et al.
Circulation research, 112(4), 689-697 (2013-01-09)
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by mutations in cardiac ryanodine receptor (RyR2) or calsequestrin (Casq2) genes. Sinoatrial node dysfunction associated with CPVT may increase the risk for ventricular arrhythmia (VA). To test the hypothesis that CPVT is suppressed

全球贸易项目编号

货号GTIN
295116-PZ04061837935695
295116-50L-EU04061838084194
295116-50L04061826642030

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