11480
壬二酸
technical, ~85% (GC)
别名:
杜鹃花酸
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
线性分子式:
HO2C(CH2)7CO2H
化学文摘社编号:
分子量:
188.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-669-1
Beilstein/REAXYS Number:
1101094
MDL number:
Assay:
~85% (GC)
vapor density
6.5 (vs air)
Quality Segment
vapor pressure
<1 mmHg ( 20 °C)
grade
technical
assay
~85% (GC)
bp
286 °C/100 mmHg (lit.)
mp
109-111 °C (lit.)
functional group
carboxylic acid
SMILES string
OC(=O)CCCCCCCC(O)=O
InChI
1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChI key
BDJRBEYXGGNYIS-UHFFFAOYSA-N
General description
Azelaic acid (Nonanedioic acid) is a naturally occurring saturated, nonphenolic compound isolated from cultures Pityrosporum ovale. It is a therapeutic agent with well-known antibacterial properties.
Application
- A phase 3 randomized, double-blind, vehicle-controlled trial of azelaic acid foam 15% in the treatment of papulopustular rosacea: This study evaluates the efficacy and safety of a 15% azelaic acid foam in treating rosacea, demonstrating significant improvements in disease severity (Draelos et al., 2015).
- Comparison of the characteristics of transfersomes and protransfersomes containing azelaic acid: This research compares the properties of transfersome formulations with azelaic acid, highlighting their potential for enhanced delivery in dermatological applications (Rahmi and Pangesti, 2018).
- Enhancing the bioconversion of azelaic acid to its derivatives by response surface methodology: This article discusses optimizing the production of azelaic acid derivatives, which are crucial for cosmetic and pharmaceutical applications (Khairudin et al., 2018).
- Azelaic acid: a bio-based building block for biodegradable polymers: The study explores azelaic acid as a sustainable precursor for producing biodegradable polymers, pertinent to material science (Todea et al., 2021).
- Preparation and evaluation of azelaic acid topical microemulsion formulation: in vitro and in vivo study: This research presents a microemulsion formulation of azelaic acid, assessing its stability and skin permeability, critical for topical therapeutic applications (Hung et al., 2021).
Biochem/physiol Actions
Azelaic acid is a potent inhibitor of 5α-reductase activity. It is a reversible competitive inhibitor of thioredoxin reductase in human melanoma cells.
Still not finding the right product?
Explore all of our products under 壬二酸
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
410.0 °F - closed cup
flash_point_c
210 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)