11542
L -氮杂环丁烷-2-羧酸
purum, ≥98.0% (NT)
别名:
( S )-氮杂环丁烷-2-羧酸
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关于此项目
经验公式（希尔记法）:
C4H7NO2
化学文摘社编号:
分子量:
101.10
EC Number:
218-362-5
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
80680
MDL number:
grade
purum
assay
≥98.0% (NT)
optical activity
[α]20/D −123±2°, c = 4% in H2O
mp
~215 °C (dec.)
SMILES string
OC(=O)[C@@H]1CCN1
InChI
1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
InChI key
IADUEWIQBXOCDZ-VKHMYHEASA-N
Biochem/physiol Actions
L-氮杂环丁烷-2-羧酸是胶原合成抑制剂，具有抗血管生成作用。
L-氮杂环丁烷-2-羧酸是胶原合成抑制剂，具有抗血管生成作用。它是 L-脯氨酸的四元环类似物，当掺入它而不是脯氨酸时导致蛋白质错构。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Preparation of mugineic acid; 4-Oxidation to the corresponding lactam
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Y. Hamada et al.
The Journal of Organic Chemistry, 51, 5489-5489 (1986)
K. Tanaka et al.
Heterocycles, 24, 2539-2539 (1986)
Kaoru Iinoya et al.
Biotechnology and bioengineering, 103(2), 341-352 (2009-01-27)
The budding yeast Saccharomyces cerevisiae Sigma1278b has the MPR1 gene, which confers resistance to the proline analogue azetidine-2-carboxylate (AZC). This gene encodes an N-acetyltransferase Mpr1 that detoxifies AZC, and the homologous genes have been found in many yeasts. Recently, we
B A Kirby et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 14(9), 5687-5693 (1994-09-01)
A68, or PHF-tau, is an abnormally phosphorylated form of the microtubule-associated protein tau, which is a primary protein constituent of paired helical filaments (PHFs) and, ultimately, of Alzheimer's disease-associated neurofibrillary tangles (NFTs). Previously, we have shown that in heat-shocked neuronal
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