12650
苯磺酰肼
technical, ≥90% (NT)
别名:
BSH, 发乳剂 BSH, 发泡剂 BSH
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关于此项目
线性分子式:
C6H5SO2NHNH2
化学文摘社编号:
分子量:
172.20
EC Number:
201-255-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
640079
MDL number:
grade
technical
assay
≥90% (NT)
mp
101-103 °C (lit.)
SMILES string
NNS(=O)(=O)c1ccccc1
InChI
1S/C6H8N2O2S/c7-8-11(9,10)6-4-2-1-3-5-6/h1-5,8H,7H2
InChI key
VJRITMATACIYAF-UHFFFAOYSA-N
Application
Benzenesulfonylhydrazine (Benzenesulfonyl hydrazide) has been used in the synthesis of 13-arylsulfonylhydrazones of doxorubicin.
Benzenesulfonyl hydrazide has been used in the synthesis of a series of novel 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines for their use as potential HIV-1 integrase (IN) inhibitors.
Other Notes
用于通过与腙反应，将羰基化合物转化为乙烯基硅烷的试剂。
Zdzisław Brzozowski et al.
European journal of medicinal chemistry, 44(1), 190-196 (2008-04-09)
A series of novel 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines 15-28 as potential HIV-1 integrase (IN) inhibitors have been synthesized by the reduction of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines 1-14 with benzenesulfonyl hydrazide. All the compounds 15-28 inhibited IN mediated strand transfer reaction with IC(50) values ranging from 3
T.H. Chan et al.
Synthesis, 801-801 (1976)
Synthesis of an anthracyclinone bearing an unprecedented aromatic ring-fused bridgehead-hydroxylated bicyclo [3.1. 1] heptanol.
Tetrahedron Letters, 48(42), 7440-7443 (2007)
C.A. Paquette et al.
The Journal of Organic Chemistry, 45, 3017-3017 (1980)
Contact dermatitis from benzene sulphonyl hydrazide.
J S English et al.
Contact dermatitis, 14(3), 183-183 (1986-03-01)
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