14405
(+)-生物素N-羟基琥珀酰亚胺酯
≥95% (HPLC)
别名:
(+)-生物素N-琥珀酰亚胺酯, d-生物素NHS酯, BNHS, N-琥珀酰亚胺基D-生物素, N-羟基琥珀酰亚胺生物素, NHS-生物素, 生物素-N-羟基琥珀酰亚胺
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关于此项目
经验公式(希尔记法):
C14H19N3O5S
化学文摘社编号:
分子量:
341.38
Beilstein:
4720781
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
生物来源
synthetic
质量水平
方案
≥95% (HPLC)
表单
powder
旋光性
[α]20/D +53±1°, c = 1% in DMF
颜色
white to off-white
mp
212-214 °C
储存温度
−20°C
SMILES字符串
[H][C@]12CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
InChI
1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1
InChI key
YMXHPSHLTSZXKH-RVBZMBCESA-N
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其他说明
Activated biotin, generally used for attaching biotin to amino acids, peptides and proteins; Review: The use of the avidin-biotin complex as a tool in molecular biology; On-resin biotinylation of chemically synthesized proteins for one-step purification
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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T J Lobl et al.
Analytical biochemistry, 170(2), 502-511 (1988-05-01)
A general, convenient, one-step purification procedure for chemically synthesized proteins present in low yields using on-resin biotinylation is reported. The protein, terminally deprotected and neutralized on-resin, is stirred in dimethylformamide and then biotinylated with N-hydroxysuccinimidobiotin (2 mg/mg protein on-resin) for
K. Hoffmann et al.
Journal of the American Chemical Society, 100, 3585-3585 (1978)
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Journal of molecular signaling, 4, 6-6 (2009-09-04)
Glucocorticoid hormones (GCs) induce apoptosis of leukemic T-cells by transcriptional regulation via the GC receptor, GR. In the human leukemic CEM cell culture model, RCAN1 has been identified as one of the genes that is specifically upregulated only in the
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