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Merck
CN

14405

Sigma-Aldrich

(+)-生物素N-羟基琥珀酰亚胺酯

≥95% (HPLC)

别名:

(+)-生物素N-琥珀酰亚胺酯, d-生物素NHS酯, BNHS, N-琥珀酰亚胺基D-生物素, N-羟基琥珀酰亚胺生物素, NHS-生物素, 生物素-N-羟基琥珀酰亚胺

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关于此项目

经验公式(希尔记法):
C14H19N3O5S
化学文摘社编号:
分子量:
341.38
Beilstein:
4720781
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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生物来源

synthetic

质量水平

方案

≥95% (HPLC)

表单

powder

旋光性

[α]20/D +53±1°, c = 1% in DMF

颜色

white to off-white

mp

212-214 °C

储存温度

−20°C

SMILES字符串

[H][C@]12CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI

1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1

InChI key

YMXHPSHLTSZXKH-RVBZMBCESA-N

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其他说明

Activated biotin, generally used for attaching biotin to amino acids, peptides and proteins; Review: The use of the avidin-biotin complex as a tool in molecular biology; On-resin biotinylation of chemically synthesized proteins for one-step purification

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Maria Livia Bernardi et al.
PloS one, 6(11), e27856-e27856 (2011-11-25)
Food allergy is increasingly common worldwide. Tools for allergy diagnosis measuring IgE improved much since allergenic molecules and microarrays started to be used. IgE response toward allergens belonging to the same group of molecules has not been comprehensively explored using
Ran Li et al.
Molecular cancer therapeutics, 17(1), 169-182 (2017-09-25)
In response to cellular stress, phosphatidylserine is exposed on the outer membrane leaflet of tumor blood vessels and cancer cells, motivating the development of phosphatidylserine-specific therapies. The generation of drug-conjugated phosphatidylserine-targeting agents represents an unexplored therapeutic approach, for which antitumor
T J Lobl et al.
Analytical biochemistry, 170(2), 502-511 (1988-05-01)
A general, convenient, one-step purification procedure for chemically synthesized proteins present in low yields using on-resin biotinylation is reported. The protein, terminally deprotected and neutralized on-resin, is stirred in dimethylformamide and then biotinylated with N-hydroxysuccinimidobiotin (2 mg/mg protein on-resin) for
K. Hoffmann et al.
Journal of the American Chemical Society, 100, 3585-3585 (1978)
Yasuko Hirakawa et al.
Journal of molecular signaling, 4, 6-6 (2009-09-04)
Glucocorticoid hormones (GCs) induce apoptosis of leukemic T-cells by transcriptional regulation via the GC receptor, GR. In the human leukemic CEM cell culture model, RCAN1 has been identified as one of the genes that is specifically upregulated only in the

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