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Merck
CN

14405

(+)-生物素N-羟基琥珀酰亚胺酯

≥95% (HPLC)

别名:

(+)-生物素N-琥珀酰亚胺酯, d-生物素NHS酯, BNHS, N-琥珀酰亚胺基D-生物素, N-羟基琥珀酰亚胺生物素, NHS-生物素, 生物素-N-羟基琥珀酰亚胺

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经验公式(希尔记法):
C14H19N3O5S
化学文摘社编号:
分子量:
341.38
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
4720781
MDL number:
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SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI

1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1

InChI key

YMXHPSHLTSZXKH-RVBZMBCESA-N

biological source

synthetic

assay

≥95% (HPLC)

form

powder

optical activity

[α]20/D +53±1°, c = 1% in DMF

color

white to off-white

mp

212-214 °C

storage temp.

−20°C

Quality Level

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Other Notes

Activated biotin, generally used for attaching biotin to amino acids, peptides and proteins; Review: The use of the avidin-biotin complex as a tool in molecular biology; On-resin biotinylation of chemically synthesized proteins for one-step purification

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Maria Livia Bernardi et al.
PloS one, 6(11), e27856-e27856 (2011-11-25)
Food allergy is increasingly common worldwide. Tools for allergy diagnosis measuring IgE improved much since allergenic molecules and microarrays started to be used. IgE response toward allergens belonging to the same group of molecules has not been comprehensively explored using
T J Lobl et al.
Analytical biochemistry, 170(2), 502-511 (1988-05-01)
A general, convenient, one-step purification procedure for chemically synthesized proteins present in low yields using on-resin biotinylation is reported. The protein, terminally deprotected and neutralized on-resin, is stirred in dimethylformamide and then biotinylated with N-hydroxysuccinimidobiotin (2 mg/mg protein on-resin) for
Tue W Kragstrup et al.
Arthritis research & therapy, 16(1), R42-R42 (2014-02-05)
Spondyloarthritis (SpA) comprises a group of diseases often associated with HLA-B27 and characterized by inflammation of the entheses and joints of the axial skeleton. The inflammatory process in SpA is presumably driven by innate immune cells but is still poorly
K. Hoffmann et al.
Journal of the American Chemical Society, 100, 3585-3585 (1978)
Yasuko Hirakawa et al.
Journal of molecular signaling, 4, 6-6 (2009-09-04)
Glucocorticoid hormones (GCs) induce apoptosis of leukemic T-cells by transcriptional regulation via the GC receptor, GR. In the human leukemic CEM cell culture model, RCAN1 has been identified as one of the genes that is specifically upregulated only in the

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