16499
7-异丙氧基-3-苯基-4H-1-苯并吡喃-4-酮
analytical standard
别名:
（依普黄酮）
等级
analytical standard
质量水平
方案
≥98.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
116-120 °C (lit.)
包装形式
neat
SMILES字符串
CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1
InChI
1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
InChI key
SFBODOKJTYAUCM-UHFFFAOYSA-N
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一般描述
Ipriflavone, a flavonoid derivative of the natural isoflavone compound, plays a role in the mitochondrial phosphorylation and exhibits growth-promoting activity.
应用
Ipriflavone can be used as an analytical standard for the determination of the analyte in human and animal biological samples by liquid chromatography (LC) based methods.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Determination of ipriflavone and its synthetic impurities by high-performance liquid chromatography using diode-array detection
Sustacha K, et al.
Journal of Chromatography A, 719(1), 245-250 (1996)
Simultaneous determination of ipriflavone and its main metabolites M1 and M5 in human plasma by liquid chromatography with tandem mass spectrometry
Ji HY, et al.
Analytical Letters, 38(1), 99-110 (2005)
Hye J Chung et al.
The Journal of pharmacy and pharmacology, 58(4), 449-457 (2006-04-07)
In order to find out what types of the hepatic microsomal cytochrome P450 (CYP) isozymes are involved in the metabolism of ipriflavone, ipriflavone at a dose of 20 mg kg(-1) (or 15 mg kg(-1)) was infused in male Sprague-Dawley rats.
Disposition of ipriflavone (TC-80) in rats and dogs.
Yoshida K, et al.
Radioisotopes, 34(11), 618-623 (1985)
H J Chung et al.
Research in veterinary science, 85(1), 149-155 (2007-10-09)
It has been reported that ipriflavone was primarily metabolized via hepatic microsomal cytochrome P450 (CYP) 1A1/2 and 2C11 in rats, and the expression of hepatic CYP1A2 and 2C11 was not changed in rats with water deprivation for 72h compared to
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