17081
Fura-2 LeakRes (AM)
≥95% (TLC)
别名:
Fura PE 3-AM
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关于此项目
经验公式（希尔记法）:
C55H63N5O29
化学文摘社编号:
分子量:
1258.10
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
assay
≥95% (TLC)
solubility
DMSO: soluble
fluorescence
λex 335 nm; λem 495 nm in 0.1 M Tris pH 8.0, esterase; 10 mM Ca2+
suitability
suitable for fluorescence
storage temp.
−20°C
SMILES string
CC(=O)OCOC(=O)CN1CCN(CC1)C(=O)CCc2ccc(N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c(OCCOc3cc4cc(oc4cc3N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c5ncc(o5)C(=O)OCOC(C)=O)c2
InChI
1S/C55H63N5O29/c1-33(61)76-27-82-49(68)22-57-11-13-58(14-12-57)48(67)10-8-39-7-9-41(59(23-50(69)83-28-77-34(2)62)24-51(70)84-29-78-35(3)63)44(17-39)74-15-16-75-45-18-40-19-46(54-56-21-47(89-54)55(73)87-32-81-38(6)66)88-43(40)20-42(45)60(25-52(71)85-30-79-36(4)64)26-53(72)86-31-80-37(5)65/h7,9,17-21H,8,10-16,22-32H2,1-6H3
InChI key
CGAZNAYDEAJZHQ-UHFFFAOYSA-N
Application
Fura 2 is one of the most widely used calcium indicators for ratiometric measurement and is highly suitable for digital imaging microscopy.
Features and Benefits
Pale yellow gum. Cell permeable acetoxymethyl ester (AM) derivative of Fura-PE3 with spectral properties similar to the parent compound.
Other Notes
Cell permeable ester of fluorescent calcium probe; abs.: λmax 364 nm; em.: λmax 502 nm
法规信息
新产品
此项目有
F Abe et al.
British journal of pharmacology, 116(7), 3000-3004 (1995-12-01)
1. To examine whether cytosolic Ca2+ in smooth muscle cells distributes evenly, cytosolic Ca2+ levels were measured with two different Ca2+ indicators in the ferret isolated portal vein; a fluorescent indicator, fura-PE3, that shows the average Ca2+ level, and a
E P Milner et al.
The Journal of laboratory and clinical medicine, 131(1), 49-62 (1998-02-06)
High shear stress in narrowed arteries causes von Willebrand factor (vWf) to bind to its platelet receptor, glycoprotein Ib (GpIb). This binding is reported to promote an increase in intracellular free calcium concentration ((Ca2+)i), which may be responsible for platelet
Entaz Bahar et al.
International journal of molecular sciences, 21(20) (2020-10-21)
Ovarian cancer (OC) is the most lethal of the gynecologic cancers, and platinum-based treatment is a part of the standard first-line chemotherapy regimen. However, rapid development of acquired cisplatin resistance remains the main cause of treatment failure, and the underlying