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Merck
CN

17860

2-溴辛酸

purum, ≥97.0% (GC)

别名:

2-Bromocaprylic acid

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关于此项目

线性分子式:
CH3(CH2)5CH(Br)COOH
化学文摘社编号:
分子量:
223.11
EC Number:
220-079-7
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
1760958
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grade

purum

assay

≥97.0% (GC)

refractive index

n20/D 1.471

bp

140 °C/5 mmHg (lit.)

density

1.278 g/mL at 25 °C (lit.)

SMILES string

CCCCCCC(Br)C(O)=O

InChI

1S/C8H15BrO2/c1-2-3-4-5-6-7(9)8(10)11/h7H,2-6H2,1H3,(H,10,11)

InChI key

GTGTXZRPJHDASG-UHFFFAOYSA-N

Biochem/physiol Actions

2-Bromooctanoic acid is a fatty acyl coenzyme A synthetase (FadD) inhibitor. It also inhibits β-oxidation enzymes in animal cells.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Danis et al.
The Journal of pharmacology and experimental therapeutics, 219(2), 383-388 (1981-11-01)
Mixed-function oxidation of p-nitroanisole in isolated perfused livers from fasted rats was studied in the presence and absence of 2-bromooctanoate, an inhibitor of the beta-oxidation of acyl CoA compounds. These experiments were designed to test the hypothesis that reducing equivalents
Umi S Ramli et al.
The FEBS journal, 272(22), 5764-5770 (2005-11-11)
We applied metabolic control analysis to the Kennedy pathway for triacylglycerol formation in tissue cultures from the important oil crops, olive (Olea europaea L.) and oil palm (Elaeis guineensis Jacq.). When microsomal fractions were incubated at 30 degrees C rather
R Hertz et al.
The Biochemical journal, 245(2), 387-392 (1987-07-15)
1. The induction of peroxisomal beta-oxidation activities by bezafibrate in cultured rat hepatocytes and in the rat in vivo was prevented by inhibitors of carnitine acyltransferase, e.g. 2-bromopalmitate, 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate or 2-tetradecylglycidic acid. 2. The prevention of peroxisomal proliferation by carnitine
I A Finnie et al.
Gut, 36(1), 93-99 (1995-01-01)
The effects of sodium butyrate and sodium bromo-octanoate (an inhibitor of beta oxidation) on colonic mucus glycoprotein (mucin) synthesis have been assessed using tissue from colonic resection samples. Epithelial biopsy specimens were incubated for 16 hours in RPMI 1640 with
2-Bromooctanoate.
B M Raaka et al.
Methods in enzymology, 72, 559-577 (1981-01-01)

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