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Merck
CN

17970

2,4′-二溴苯乙酮

puriss., ≥98.5% (HPLC)

别名:

4′-溴苯甲酰甲基溴

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关于此项目

线性分子式:
BrC6H4COCH2Br
化学文摘社编号:
分子量:
277.94
EC Number:
202-783-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
607604
MDL number:
Assay:
≥98.5% (HPLC)
Form:
solid
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InChI key

FKJSFKCZZIXQIP-UHFFFAOYSA-N

InChI

1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

SMILES string

BrCC(=O)c1ccc(Br)cc1

grade

puriss.

assay

≥98.5% (HPLC)

form

solid

mp

108-110 °C (lit.), 108-112 °C

Gene Information

human ... PLA2G2A(5320)
rat ... Pla2g2a(29692)

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General description

The effect of 2,4′-dibromoacetophenone on rat seminiferous tubules in vitro was studied.

Other Notes

修饰蛋白质中组氨酸残基

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Taomin Huang et al.
Journal of pharmaceutical and biomedical analysis, 41(2), 644-648 (2006-01-18)
A simple, rapid and sensitive high-performance liquid chromatographic method for the simultaneous determination of captopril and hydrochlorothiazide in human plasma samples was developed. Captopril was derivatized with 2,4'-dibromoacetophenone (pBPB) to form a captopril-pBPB adduct. From acidified serum plasma samples, the
J Fohlman et al.
European journal of biochemistry, 94(2), 531-540 (1979-03-01)
Treatment of taipoxin with p-bromophenacyl bromide resulted in modification of single histidine residues in the alpha and beta subunits. The modification decreased the neurotoxicity (lethality) 350-fold, but the inhibitory action on high-affinity choline transport was reduced only threefold. The phospholipase
C H Farr et al.
Journal of reproduction and fertility, 58(1), 37-42 (1980-01-01)
The effects of prostaglandin (PG) F-2 alpha and E-2, cyclic GMP, testosterone and 2,4'-dibromoacetophenone (DBA) on rat seminiferous tubules in vitro were ascertained by measuring contractile frequency, size of contractions and tone (tubular diameter). PGF-2 alpha (10(-9)--10(-5) M) increased frequency
C C Yang et al.
Biochimica et biophysica acta, 614(2), 373-388 (1980-08-07)
Phospholipase A2 from Naja nigricollis venom was separated into three fractions by chromatography on a column of CM-Sephadex C-25. The pI values of fractions CMS-5, CMS-6 and CMS-9 were determined to be 7.6, 8.3 and 10.6, respectively. Fraction CMS-9 was
Zhuo-Jia Chen et al.
Seizure, 21(2), 110-117 (2011-11-08)
Valproic acid (VPA) is a well-established anticonvulsant drug that has been increasingly used in the treatment of many forms of generalized epilepsy. Although there are many reports of adverse effects of VPA, studies focusing on the concentration-response relationships of VPA

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