17970
2,4′-二溴苯乙酮
puriss., ≥98.5% (HPLC)
别名:
4′-溴苯甲酰甲基溴
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线性分子式:
BrC6H4COCH2Br
化学文摘社编号:
分子量:
277.94
EC Number:
202-783-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
607604
MDL number:
Assay:
≥98.5% (HPLC)
Form:
solid
InChI key
FKJSFKCZZIXQIP-UHFFFAOYSA-N
InChI
1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
SMILES string
BrCC(=O)c1ccc(Br)cc1
grade
puriss.
assay
≥98.5% (HPLC)
form
solid
mp
108-110 °C (lit.), 108-112 °C
Gene Information
human ... PLA2G2A(5320)
rat ... Pla2g2a(29692)
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General description
The effect of 2,4′-dibromoacetophenone on rat seminiferous tubules in vitro was studied.
Other Notes
修饰蛋白质中组氨酸残基
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Taomin Huang et al.
Journal of pharmaceutical and biomedical analysis, 41(2), 644-648 (2006-01-18)
A simple, rapid and sensitive high-performance liquid chromatographic method for the simultaneous determination of captopril and hydrochlorothiazide in human plasma samples was developed. Captopril was derivatized with 2,4'-dibromoacetophenone (pBPB) to form a captopril-pBPB adduct. From acidified serum plasma samples, the
J Fohlman et al.
European journal of biochemistry, 94(2), 531-540 (1979-03-01)
Treatment of taipoxin with p-bromophenacyl bromide resulted in modification of single histidine residues in the alpha and beta subunits. The modification decreased the neurotoxicity (lethality) 350-fold, but the inhibitory action on high-affinity choline transport was reduced only threefold. The phospholipase
C H Farr et al.
Journal of reproduction and fertility, 58(1), 37-42 (1980-01-01)
The effects of prostaglandin (PG) F-2 alpha and E-2, cyclic GMP, testosterone and 2,4'-dibromoacetophenone (DBA) on rat seminiferous tubules in vitro were ascertained by measuring contractile frequency, size of contractions and tone (tubular diameter). PGF-2 alpha (10(-9)--10(-5) M) increased frequency
C C Yang et al.
Biochimica et biophysica acta, 614(2), 373-388 (1980-08-07)
Phospholipase A2 from Naja nigricollis venom was separated into three fractions by chromatography on a column of CM-Sephadex C-25. The pI values of fractions CMS-5, CMS-6 and CMS-9 were determined to be 7.6, 8.3 and 10.6, respectively. Fraction CMS-9 was
Zhuo-Jia Chen et al.
Seizure, 21(2), 110-117 (2011-11-08)
Valproic acid (VPA) is a well-established anticonvulsant drug that has been increasingly used in the treatment of many forms of generalized epilepsy. Although there are many reports of adverse effects of VPA, studies focusing on the concentration-response relationships of VPA
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