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Merck
CN

17970

2,4′-二溴苯乙酮

puriss., ≥98.5% (HPLC)

别名:

4′-溴苯甲酰甲基溴

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关于此项目

线性分子式:
BrC6H4COCH2Br
化学文摘社编号:
分子量:
277.94
EC Number:
202-783-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
607604
MDL number:
Assay:
≥98.5% (HPLC)
Form:
solid
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InChI key

FKJSFKCZZIXQIP-UHFFFAOYSA-N

InChI

1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

SMILES string

BrCC(=O)c1ccc(Br)cc1

grade

puriss.

assay

≥98.5% (HPLC)

form

solid

mp

108-110 °C (lit.), 108-112 °C

Gene Information

human ... PLA2G2A(5320)
rat ... Pla2g2a(29692)

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General description

The effect of 2,4′-dibromoacetophenone on rat seminiferous tubules in vitro was studied.

Other Notes

修饰蛋白质中组氨酸残基

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Taomin Huang et al.
Journal of pharmaceutical and biomedical analysis, 41(2), 644-648 (2006-01-18)
A simple, rapid and sensitive high-performance liquid chromatographic method for the simultaneous determination of captopril and hydrochlorothiazide in human plasma samples was developed. Captopril was derivatized with 2,4'-dibromoacetophenone (pBPB) to form a captopril-pBPB adduct. From acidified serum plasma samples, the
H M Verheij et al.
Biochemistry, 19(4), 743-750 (1980-02-19)
It is known that His-48 is part of the active center in pancreatic phospholipase. To further elucidate the role of histidine-48 in the active center of pancreatic phospholipase A2, we have modified the enzyme with a number of bromo ketones
J Fohlman et al.
European journal of biochemistry, 94(2), 531-540 (1979-03-01)
Treatment of taipoxin with p-bromophenacyl bromide resulted in modification of single histidine residues in the alpha and beta subunits. The modification decreased the neurotoxicity (lethality) 350-fold, but the inhibitory action on high-affinity choline transport was reduced only threefold. The phospholipase
C H Farr et al.
Journal of reproduction and fertility, 58(1), 37-42 (1980-01-01)
The effects of prostaglandin (PG) F-2 alpha and E-2, cyclic GMP, testosterone and 2,4'-dibromoacetophenone (DBA) on rat seminiferous tubules in vitro were ascertained by measuring contractile frequency, size of contractions and tone (tubular diameter). PGF-2 alpha (10(-9)--10(-5) M) increased frequency
C C Yang et al.
Biochimica et biophysica acta, 614(2), 373-388 (1980-08-07)
Phospholipase A2 from Naja nigricollis venom was separated into three fractions by chromatography on a column of CM-Sephadex C-25. The pI values of fractions CMS-5, CMS-6 and CMS-9 were determined to be 7.6, 8.3 and 10.6, respectively. Fraction CMS-9 was

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