InChI key
NYPYPOZNGOXYSU-UHFFFAOYSA-N
InChI
1S/C5H4BrN/c6-5-2-1-3-7-4-5/h1-4H
SMILES string
Brc1cccnc1
grade
purum
assay
≥97.0% (GC)
bp
173 °C (lit.)
density
1.64 g/mL at 25 °C (lit.)
Application
3-Bromopyridine was used in the synthesis of cis-1-methyl-1,2,3,3a,4,8b-hexahydropyrrolo[3,2-f]pyrindine (a nicotine analog). It was also used in the preparation of 3-pyridylboronic acid.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
125.6 °F - closed cup
flash_point_c
52 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Wenjie Li et al.
The Journal of organic chemistry, 67(15), 5394-5397 (2002-07-20)
3-Pyridylboronic acid was prepared in high yield and bulk quantity from 3-bromopyridine via a protocol of lithium-halogen exchange and "in situ quench". This technique was further studied and evaluated on other aryl halides in the preparation of arylboronic acids.
Hongbin Zhai et al.
Organic letters, 4(25), 4385-4386 (2002-12-06)
[reaction: see text] The title compound, 2, has been synthesized in 45% overall yield in six steps from 3-bromopyridine. The hexahydropyrrolo[3,2-f]pyrindine skeleton was constructed from key intermediate 5, via intramolecular azomethine ylide-alkene [3 + 2] cycloaddition. The present work constitutes
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