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Merck
CN

18800

马钱子碱

purum, ≥97.0% (TLC)

别名:

10,11-二甲氧基马钱子碱

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关于此项目

经验公式(希尔记法):
C23H26N2O4
化学文摘社编号:
分子量:
394.46
EC Number:
206-614-7
UNSPSC Code:
12352000
MDL number:
Beilstein/REAXYS Number:
63046
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grade

purum

assay

≥97.0% (TLC)

optical activity

[α]20/D −120±10°, c = 2.5% in chloroform

impurities

~3% water

mp

175-178 °C (dec.) (lit.), 176-179 °C

SMILES string

[H][C@@]12CC(=O)N3c4cc(OC)c(OC)cc4[C@]56CC[N@H]7CC(=CCO1)[C@]([H])(C[C@@H]57)[C@]2([H])[C@]36[H]

InChI

1S/C23H26N2O4/c1-27-16-8-14-15(9-17(16)28-2)25-20(26)10-18-21-13-7-19-23(14,22(21)25)4-5-24(19)11-12(13)3-6-29-18/h3,8-9,13,18-19,21-22H,4-7,10-11H2,1-2H3/t13-,18-,19-,21-,22-,23+/m0/s1

InChI key

RRKTZKIUPZVBMF-IBTVXLQLSA-N

Application

羧酸的拆分试剂


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pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Aquatic Chronic 3

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Jian-Min Qin et al.
International journal of nanomedicine, 7, 369-379 (2012-02-16)
Hepatocellular carcinoma is difficult to diagnose early, and most patients are already in the late stages of the disease when they are admitted to hospital. The total 5-year survival rate is less than 5%. Recent studies have showed that brucine
Yanwen Liu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2714-2719 (2011-08-23)
A selective, simple and efficient method-ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed for determination of two toxic alkaloids, namely strychnine and brucine in mice plasma. The UPLC separation was carried out using a 1.7 μm BEH C(18) column (50
Jun Chen et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(5), 721-729 (2011-05-03)
A simple and low-cost HPLC method with UV absorbance detection was developed and validated to simultaneously determine strychnine and brucine, the most abundant alkaloids in the processed Semen Strychni, in rat tissues (kidney, liver, spleen, lung, heart, stomach, small intestine