InChI key
DKACXUFSLUYRFU-UHFFFAOYSA-N
InChI
1S/C5H12N2O2/c1-5(2,3)9-4(8)7-6/h6H2,1-3H3,(H,7,8)
SMILES string
O=C(NN)OC(C)(C)C
grade
purum
assay
≥98.0% (GC)
bp
63-65 °C/0.1 mmHg (lit.)
mp
38-42 °C, 39-42 °C (lit.)
application(s)
peptide synthesis
Other Notes
制备 BOC-叠氮化物的原料,BOC-叠氮化物是引入 BOC 氨基保护的一种试剂;E. Wünsch in Houben-Weyl, Vol. 15/1, Synthese von grossen Peptiden, p. 112.;也可用作合成磺酰肼和羧基肼的试剂
This product has been replaced by B91005-ALDRICH | tert-Butyl carbazate 98%
M.S. Gordon et al.
Synthesis, 244-244 (1980)
Martina Bruna Violatto et al.
ACS nano, 13(4), 4410-4423 (2019-03-19)
Steroids are the standard therapy for autoimmune hepatitis (AIH) but the long-lasting administration is hampered by severe side effects. Methods to improve the tropism of the drug toward the liver are therefore required. Among them, conjugation to nanoparticles represents one
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Jeong-A Yang et al.
Acta biomaterialia, 12, 174-182 (2014-10-12)
Liver fibrosis is a chronic liver disease caused by viral infection and/or metabolic, genetic and cholestatic disorders. The inhibition of hepatic stellate cell (HSC) activation and the selective apoptosis of activated HSCs can be a good strategy to treat liver
Joshua O Sestak et al.
The AAPS journal, 16(6), 1185-1193 (2014-09-07)
Presentation of antigen with immune stimulating "signal" has been a cornerstone of vaccine design for decades. Here, the antigen plus immune "signal" of vaccines is modified to produce antigen-specific immunotherapies (antigen-SITs) that can potentially reprogram the immune response toward tolerance
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