19772
(R)-二氢硫辛酸
analytical standard
别名:
(R)-6,8-二巯基辛酸, (R)-二氢-α-硫辛酸, R-DHLA
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关于此项目
经验公式（希尔记法）:
C8H16O2S2
化学文摘社编号:
分子量:
208.34
UNSPSC Code:
85151701
MDL number:
Beilstein/REAXYS Number:
1722776
SMILES string
OC(=O)CCCC[C@@H](S)CCS
grade
analytical standard
assay
≥95.0% (HPLC)
optical activity
[α]/D -11±2°, c = 1 in ethanol
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
food and beverages
personal care
storage temp.
2-8°C
Biochem/physiol Actions
R-DHLA 可使抗氧化剂维生素 C、硫氧还蛋白和谷胱甘肽再生，并且它们又可以让维生素 E 再生。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
B C Scott et al.
Free radical research, 20(2), 119-133 (1994-02-01)
A detailed evaluation of the antioxidant and pro-oxidant properties of lipoic acid (LA) and dihydrolipoic acid (DHLA) was performed. Both compounds are powerful scavengers of hypochlorous acid, able to protect alpha 1-antiproteinase against inactivation by HOCl. LA was a powerful
J H Prehn et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 12(1), 78-87 (1992-01-01)
It has been shown in vitro that dihydrolipoate (DL-6,8-dithioloctanoic acid) has antioxidant activity against microsomal lipid peroxidation. We tested dihydrolipoate for its neuroprotective activity using models of hypoxic and excitotoxic neuronal damage in vitro and rodent models of cerebral ischemia
H Kataoka
Journal of chromatography. B, Biomedical sciences and applications, 717(1-2), 247-262 (1998-12-01)
The analysis of lipoic acid and related compounds, such as its reduced form dihydrolipoic acid, its amide form lipoamide and other analogues, in biological and food samples is important in biochemistry, nutritional and clinical chemistry. This review summarizes the chromatographic
Arjumand I Durrani et al.
Journal of pharmaceutical and biomedical analysis, 45(4), 694-699 (2007-09-21)
Alpha-lipoic acid is an antioxidant used both in the prevention and treatment of various oxidative stress related diseases. It is an important constituent of some dietary supplements and can also be found in plant and animal sources. A rapid method
Soichiro Satoh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 854(1-2), 109-115 (2007-04-28)
The simultaneous determination of alpha-lipoic acid (LA) and DHLA (reduced form of LA) was carried out by HPLC with fluorescence detection. DHLA in the sample was first labeled with ABD-F at room temperature for 10 min and then the LA
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