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Merck
CN

19772

Supelco

(R)-二氢硫辛酸

analytical standard

别名:

(R)-6,8-二巯基辛酸, (R)-二氢-α-硫辛酸, R-DHLA

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关于此项目

经验公式(希尔记法):
C8H16O2S2
化学文摘社编号:
分子量:
208.34
Beilstein:
1722776
MDL编号:
UNSPSC代码:
85151701
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等级

analytical standard

方案

≥95.0% (HPLC)

旋光性

[α]/D -11±2°, c = 1 in ethanol

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
food and beverages
personal care

储存温度

2-8°C

SMILES字符串

OC(=O)CCCC[C@@H](S)CCS

生化/生理作用

R-DHLA 可使抗氧化剂维生素 C、硫氧还蛋白和谷胱甘肽再生,并且它们又可以让维生素 E 再生。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H Kataoka
Journal of chromatography. B, Biomedical sciences and applications, 717(1-2), 247-262 (1998-12-01)
The analysis of lipoic acid and related compounds, such as its reduced form dihydrolipoic acid, its amide form lipoamide and other analogues, in biological and food samples is important in biochemistry, nutritional and clinical chemistry. This review summarizes the chromatographic
J H Prehn et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 12(1), 78-87 (1992-01-01)
It has been shown in vitro that dihydrolipoate (DL-6,8-dithioloctanoic acid) has antioxidant activity against microsomal lipid peroxidation. We tested dihydrolipoate for its neuroprotective activity using models of hypoxic and excitotoxic neuronal damage in vitro and rodent models of cerebral ischemia
B C Scott et al.
Free radical research, 20(2), 119-133 (1994-02-01)
A detailed evaluation of the antioxidant and pro-oxidant properties of lipoic acid (LA) and dihydrolipoic acid (DHLA) was performed. Both compounds are powerful scavengers of hypochlorous acid, able to protect alpha 1-antiproteinase against inactivation by HOCl. LA was a powerful
Arjumand I Durrani et al.
Journal of pharmaceutical and biomedical analysis, 45(4), 694-699 (2007-09-21)
Alpha-lipoic acid is an antioxidant used both in the prevention and treatment of various oxidative stress related diseases. It is an important constituent of some dietary supplements and can also be found in plant and animal sources. A rapid method
Soichiro Satoh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 854(1-2), 109-115 (2007-04-28)
The simultaneous determination of alpha-lipoic acid (LA) and DHLA (reduced form of LA) was carried out by HPLC with fluorescence detection. DHLA in the sample was first labeled with ABD-F at room temperature for 10 min and then the LA

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