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Merck
CN

21277

钙蛋白酶抑制剂I

≥97.0% (TLC)

别名:

ALLN, Ac-LLnL-CHO, MG-101, N-乙酰基-L-亮氨酰基-L-亮氨酰基-L-正亮氨酸醛, N-乙酰基-亮氨酸-亮氨酸-正亮氨酸醛

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关于此项目

经验公式(希尔记法):
C20H37N3O4
化学文摘社编号:
分子量:
383.53
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
7656053
MDL number:
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biological source

synthetic

assay

≥97.0% (TLC)

form

powder

storage temp.

−20°C

SMILES string

[H]C(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

InChI

1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1

InChI key

FMYKJLXRRQTBOR-BZSNNMDCSA-N

Gene Information

Other Notes

Shows marked inhibition of cathepsin L


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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pedro A Moura et al.
Antimicrobial agents and chemotherapy, 53(12), 4968-4978 (2009-09-16)
Hemoglobin (Hb) degradation is essential for the growth of the intraerythrocytic stages of malarial parasites. This process, which occurs inside an acidic digestive vacuole (DV), is thought to involve the action of four aspartic proteases, termed plasmepsins (PMs). These enzymes
Justyna M Przystal et al.
Molecular oncology, 7(1), 55-66 (2012-09-07)
Bacteriophage (phage), which are viruses that infect bacteria only, have shown promise as vehicles for targeted cancer gene therapy, albeit with poor efficiency. Recently, we generated an improved version of phage vectors by incorporating cis genetic elements of adeno-associated virus
Sayuri Mizukoshi et al.
Experimental eye research, 91(3), 353-361 (2010-06-16)
The present study was performed to investigate changes of cytosolic and mitochondrial calpain activities, and effects of intravitreously injected calpain inhibitor on photoreceptor apoptosis in Royal College of Surgeon's (RCS) rats. Time courses of activities for both cytosolic and mitochondrial