21410
癸酸
≥98.0% (GC)
别名:
C10:0, NSC 5025, 癸酸, 羊蜡酸
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线性分子式:
CH3(CH2)8COOH
化学文摘社编号:
分子量:
172.26
EC Number:
206-376-4
UNSPSC Code:
12352211
PubChem Substance ID:
Beilstein/REAXYS Number:
1754556
MDL number:
InChI key
GHVNFZFCNZKVNT-UHFFFAOYSA-N
InChI
1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
SMILES string
CCCCCCCCCC(O)=O
biological source
plant
vapor pressure
15 mmHg ( 160 °C)
assay
≥98.0% (GC)
bp
123-124 °C/0.1 mmHg, 268-270 °C (lit.)
mp
27-32 °C (lit.)
density
0.893 g/mL at 25 °C (lit.)
functional group
carboxylic acid
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Biochem/physiol Actions
Decanoic acid, a medium chain fatty acid (10-carbon fatty acid), is a ligand for peroxisome proliferator activated receptor (PPAR) γ. . Decanoic acid binds and acttivates PPARγ without leading to adipogenesis .
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
296.6 °F - closed cup
flash_point_c
147 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Raghu R V Malapaka et al.
The Journal of biological chemistry, 287(1), 183-195 (2011-11-01)
Peroxisome proliferator-activated receptors (PPARα, -β/δ, and -γ) are a subfamily of nuclear receptors that plays key roles in glucose and lipid metabolism. PPARγ is the molecular target of the thiazolidinedione class of antidiabetic drugs that has many side effects. PPARγ
M Duran et al.
The Journal of pediatrics, 107(3), 397-404 (1985-09-01)
Five patients aged 7 to 21 months are described who developed attacks of coma after a short prodromal illness with diarrhea or vomiting or both. Four had concomitant hypoglycemia, and all had hypoketonemia, with excessive urinary excretion of medium-chain dicarboxylic
T M Lima et al.
Toxicology in vitro : an international journal published in association with BIBRA, 16(6), 741-747 (2002-11-09)
The fatty acids have an important role in the control of leukocyte metabolism and function. Higher concentrations of certain fatty acids, particularly polyunsaturated fatty acids (PUFAs) and volatile fatty acids, can cause cell death via apoptosis or, when concentrations are
Morteza Moradi et al.
Journal of chromatography. A, 1229, 30-37 (2012-02-07)
A new, efficient and environmentally friendly method for the analysis of parabens as model compounds was developed using solidified floating vesicular coacervative drop microextraction (SFVCDME). A supramolecular solvent consisting of vesicles of decanoic acid in the nano- and microscale regimes
G Del Vecchio et al.
Molecular pharmaceutics, 9(9), 2523-2533 (2012-07-26)
Claudin-5 is a tight junction (TJ) protein which limits the diffusion of small hydrophilic molecules. Thus, it represents a potential pharmacological target to improve drug delivery to the tissues protected by claudin-5-dependent barriers. Sodium caprate is known as an absorption
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