292664
N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt
95%
别名:
2-SPBN sodium salt, 2-Sulfonatophenyl tert-butyl nitrone sodium salt
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关于此项目
线性分子式:
NaO3SC6H4CH=N(O)C(CH3)3
化学文摘社编号:
分子量:
279.29
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
InChI
1S/C11H15NO4S.Na/c1-11(2,3)12(13)8-9-6-4-5-7-10(9)17(14,15)16;/h4-8H,1-3H3,(H,14,15,16);/q;+1/p-1/b12-8-;
SMILES string
[Na+].CC(C)(C)[N+](\[O-])=C\c1ccccc1S([O-])(=O)=O
InChI key
LAIQBHGUFDAJKL-JCTPKUEWSA-M
assay
95%
form
powder or crystals
mp
246 °C (dec.) (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Application
Water-soluble, negatively-charged spin trap used to monitor aqueous phase of SDS micelles.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
G J Wilde et al.
Journal of neurochemistry, 69(2), 883-886 (1997-08-01)
The relative roles of the superoxide and hydroxyl radicals in oxidative stress-induced neuronal damage were investigated using organotypic hippocampal slice cultures. Cultures exposed to 100 microM duroquinone, a superoxide-generating compound, for 3 h developed CA1-selective lesions over a period of
Catherine E Hobbs et al.
Pediatrics international : official journal of the Japan Pediatric Society, 50(4), 481-488 (2008-10-22)
The production of oxygen free radicals after perinatal hypoxia-ischemia is thought to play a critical role in the pathogenesis of the brain injury. Administration of anti-oxidants may thus be neuroprotective. The aim of the present study was to investigate the
Maria Molnar et al.
Upsala journal of medical sciences, 115(3), 163-168 (2010-07-20)
Hyperglycemia exacerbates focal ischemic brain damage supposedly through various mechanisms. One such mechanism is oxidative stress involving reactive oxygen and nitrogen species (RONS) production. Nitrones attenuate oxidative stress in various models of brain injury. Sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) can be
Steven L Peterson et al.
Neurotoxicology, 26(6), 969-979 (2005-05-14)
The status epilepticus (SE) induced in rats by lithium-pilocarpine (Li-pilo) shares many common features with soman-induced SE including extensive limbic neuropathology. Reactive oxygen species are hypothesized to play a role in the SE induced neuropathology and we propose that the
B Ferger et al.
European journal of pharmacology, 360(2-3), 155-163 (1998-12-16)
The potential new iron-chelator cytisine and the radical scavenger N-tert-butyl-alpha-(2-sulfophenyl) nitrone (S-PBN) were incubated in a Fenton system and hydroxyl radical formation was measured with the salicylate trapping assay. Both cytisine and S-PBN reduced hydroxyl radical formation in a concentration-dependent
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