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Merck
CN

30494

Supelco

Silydianin

analytical standard

别名:

Silidianin

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关于此项目

经验公式(希尔记法):
C25H22O10
化学文摘社编号:
分子量:
482.44
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤10.0% residual solvents (GC-HS)
≤10.0% water

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

COc1cc(ccc1O)[C@@H]2[C@H]3CO[C@]4(O)[C@H]3C(=C[C@H]2C4=O)[C@H]5Oc6cc(O)cc(O)c6C(=O)[C@@H]5O

InChI

1S/C25H22O10/c1-33-16-4-9(2-3-14(16)27)18-11-7-12(20-13(18)8-34-25(20,32)24(11)31)23-22(30)21(29)19-15(28)5-10(26)6-17(19)35-23/h2-7,11,13,18,20,22-23,26-28,30,32H,8H2,1H3/t11-,13-,18+,20+,22+,23-,25-/m1/s1

InChI key

CYGIJEJDYJOUAN-JSGXPVSSSA-N

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应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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János Fehér et al.
Orvosi hetilap, 149(51), 2413-2418 (2008-12-17)
In the treatment of chronic liver diseases adequate therapy can be chosen only in the knowledge of pathogenetic processes. In the liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver and steatohepatitis, drug and compound induced liver toxicity)
Silybin and silydianin diminish the oxidative metabolism of human polymorphonuclear neutrophils.
E Ignatowicz et al.
Acta biochimica Polonica, 44(1), 127-129 (1997-01-01)
Małgorzata Zielińska-Przyjemska et al.
Phytotherapy research : PTR, 20(2), 115-119 (2006-01-31)
The inhibitory effect of silydianin, an active constituent of Silybium marianum, on the in vitro production and release of oxidative products has been examined. Polymorphonuclear neutrophils (PMNs) play a primary role in the initiation and propagation of inflammatory responses. Their
Masumeh Khalili et al.
Cell biology international, 33(9), 988-994 (2009-06-16)
Silymarin is one of the most potent antioxidant so far developed from plant sources used as hepatoprotectants. Influence of different concentrations (0, 1, 2, 4, 6 and 8mg/50ml culture) and exposure time (24, 48, 72, 96 and 120h) of salicylic
Gagan Deep et al.
International journal of cancer, 123(1), 41-50 (2008-04-26)
Prostate cancer (PCa) is the leading cause of cancer-related deaths in men; urgent measures are warranted to lower this deadly malignancy. Silymarin is a known cancer chemopreventive agent, but the relative anticancer efficacy of its constituents is still unknown. Here

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