31095
2′-脱氧鸟苷5′-三磷酸 三钠盐
≥95% (HPLC)
别名:
dGTP-Na3
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关于此项目
经验公式（希尔记法）:
C10H13N5Na3O13P3
化学文摘社编号:
分子量:
573.13
UNSPSC Code:
12352204
PubChem Substance ID:
EC Number:
300-026-5
MDL number:
assay
≥95% (HPLC)
solubility
H2O: 50 mg/mL, clear, colorless
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)O3)C(=O)N1
InChI
1S/C10H16N5O13P3.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;;/q;3*+1/p-3/t4-,5+,6+;;;/m0.../s1
InChI key
IWGGLKOTEOCWQP-BIHLCPNHSA-K
General description
2′-脱氧鸟苷5′-三磷酸(dGTP)的结构为鸟嘌呤碱基连接脱氧核糖，糖的5′-羟基位再连接三个磷酸残基链。可用于通过DNA聚合酶合成DNA。
Application
2′-脱氧鸟苷5′-三磷酸三钠盐可用于DNA测序、PCR和其他基于DNA聚合酶的DNA合成和修复技术。
Other Notes
Substrate for DNA formation on model templates
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J E Patten et al.
Biochemistry, 23(8), 1613-1618 (1984-04-10)
The influence of the stability of base pairs formed by nearest-neighbor nucleotides on misincorporation frequency has been studied with the large fragment of DNA polymerase I, the alternating DNA copolymers, poly(dI-dC) and poly-(dG-dC), as template-primers, and dGTP, dITP, and dCTP