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Merck
CN

31545

荧光素二乙酸盐

≥98.0% (HPLC)

别名:

3,6-二乙酸荧光素, 双--O-乙酸荧光素

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关于此项目

经验公式(希尔记法):
C24H16O7
化学文摘社编号:
分子量:
416.38
EC Number:
209-877-6
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
62575
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assay

≥98.0% (HPLC)

mp

200-203 °C (lit.), 203-206 °C

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C24H16O7/c1-13(25)28-15-7-9-19-21(11-15)30-22-12-16(29-14(2)26)8-10-20(22)24(19)18-6-4-3-5-17(18)23(27)31-24/h3-12H,1-2H3

InChI key

CHADEQDQBURGHL-UHFFFAOYSA-N

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Other Notes

Fluorescent substrate for studies on intracellular interactions and membrane permeability

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Melina M Malinen et al.
Tissue engineering. Part A, 18(23-24), 2418-2425 (2012-06-21)
Current hepatocyte models do not mimic the human liver morphology and functions properly and, therefore, drug metabolism, excretion, and toxicity in the liver are inadequately predicted. In this study, we established three-dimensional (3D) hepatic cell cultures in hydrogels of peptide
David C Gillan et al.
The Science of the total environment, 419, 98-108 (2012-01-28)
Muddy sediments of the Belgian Continental Zone (BCZ) are contaminated by metals such as Co, As, Cd, Pb, and Ni. Previous studies have suggested that mineralization of phytodetritus accumulating each year on sediments might cause secondary contaminations of the overlying
Koichi Baba et al.
Journal of controlled release : official journal of the Controlled Release Society, 153(3), 278-287 (2011-05-10)
This report describes a method for enhancing the ocular penetration of eye drops using nanoparticles of hydrolyzable dye, which is similar to a prodrug approach. The entry of eye drops into the ocular globe is restricted predominantly by corneal barrier
Design of multifunctional micelle for tumor-targeted intracellular drug release and fluorescent imaging.
Weiwei Wang et al.
Advanced materials (Deerfield Beach, Fla.), 24(1), 115-120 (2011-12-07)
D F Babcock
The Journal of biological chemistry, 258(10), 6380-6389 (1983-05-25)
Fluorescein and carboxyfluorescein have found recent application as probes of intracellular pH. The present study examines several parameters required for interpretation of the spectral information derived from fluorescein and carboxyfluorescein generated intracellularly from their permeant diacetate derivatives. Coefficients were determined

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