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Merck
CN

32159

Isepamicin sulfate

VETRANAL®, analytical standard

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关于此项目

经验公式（希尔记法）:
C22H43N5O12 · xH2SO4
化学文摘社编号:
67814-76-0
分子量:
569.60 (free base basis)
PubChem Substance ID:
329754078
UNSPSC Code:
41116107
MDL number:
MFCD01683537

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InChI

1S/C22H43N5O12.H2O4S/c1-22(35)6-36-20(15(33)18(22)26-2)39-17-8(27-19(34)9(28)4-23)3-7(25)16(14(17)32)38-21-13(31)12(30)11(29)10(5-24)37-21;1-5(2,3)4/h7-18,20-21,26,28-33,35H,3-6,23-25H2,1-2H3,(H,27,34);(H2,1,2,3,4)/t7-,8+,9-,10+,11+,12-,13+,14-,15+,16+,17-,18+,20+,21+,22-;/m0./s1

InChI key

DDXRHRXGIWOVDQ-MGAUJLSLSA-N

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

Quality Level

100

General description

Isepamicin sulphate is a drug, which belongs to the aminoglycoside class of antibiotics.

Application

Isepamicin sulphate may be used as a reference standard in the separation of isepamicin sulphate from structurally related compounds using high performance liquid chromatography (HPLC), coupled with evaporative light scattering detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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分析证书(COA)

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Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testing.
Itokazu M, et al.
Biomaterials, 19(7-9), 817-819 (1998)
Determination of isepamicin sulfate and related compounds by high performance liquid chromatography using evaporative light scattering detection.
Vogel R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 24(3), 405-412 (2001)
Jing Kong et al.
Frontiers in microbiology, 11, 1718-1718 (2020-08-28)
The emergence of infections caused by bacterial pathogens that are resistant to current antibiotic therapy is a critical healthcare challenge. Aminoglycosides are natural antibiotics with broad spectrum of activity; however, their clinical use is limited due to considerable nephrotoxicity. Moreover

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