32236
Firocoxib
VETRANAL®, analytical standard
别名:
3-Cyclopropylmethoxy-4-(4-methanesulfonylphenyl)-5,5-dimethyl-5H-furan-2-one
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关于此项目
经验公式（希尔记法）:
C17H20O5S
化学文摘社编号:
分子量:
336.40
Beilstein:
8335837
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
产品线
VETRANAL®
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
veterinary
包装形式
neat
SMILES字符串
O=S(C1=CC=C(C2=C(OCC3CC3)C(OC2(C)C)=O)C=C1)(C)=O
InChI
1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
InChI key
FULAPETWGIGNMT-UHFFFAOYSA-N
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
其他说明
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Laura T Letendre et al.
American journal of veterinary research, 69(11), 1399-1405 (2008-11-05)
To determine pharmacokinetic parameters and variables, firocoxib concentrations in urine and plasma, urine-to-plasma ratios, and the urine depletion profile of firocoxib and to evaluate whether the pharmacokinetic behavior of firocoxib was governed by linear processes after multiple doses of firocoxib
L Goodman et al.
Journal of veterinary internal medicine, 23(1), 56-62 (2009-01-30)
Little is known about the effect of dual cyclooxygenase (COX) and lipoxygenase inhibition on canine gastric mucosal healing. This study compares the effects of putative dual COX and 5-lipoxygenase inhibition with that of COX-2 selective inhibition on gastric mucosal lesion
Lauretta Maggi et al.
International journal of molecular sciences, 20(12) (2019-06-27)
An electrospinning process was optimized to produce fibers of micrometric size with different combinations of polymeric and surfactant materials to promote the dissolution rate of an insoluble drug: firocoxib. Scanning Electron Microscopy (SEM) showed that only some combinations of the
A Autefage et al.
The Veterinary record, 168(23), 617-617 (2011-06-07)
Thirty-nine client-owned dogs with osteoarthritis were treated with 5 mg/kg firocoxib administered orally, once a day for 52 weeks. Veterinary examinations were performed on approximately days 0, 15, 90, 180, 270 and 360. Twenty-five dogs completed the study. The withdrawal
William G Ryan et al.
Veterinary therapeutics : research in applied veterinary medicine, 8(4), 263-271 (2008-01-10)
Veterinarians currently have a choice of six registered NSAIDs for use in the management of canine osteoarthritis. There is a need for data to clarify whether there is an increased risk of side effects occurring in the event of a
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