32236
Firocoxib
VETRANAL®, analytical standard
别名:
3-Cyclopropylmethoxy-4-(4-methanesulfonylphenyl)-5,5-dimethyl-5H-furan-2-one
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关于此项目
经验公式（希尔记法）:
C17H20O5S
化学文摘社编号:
分子量:
336.40
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8335837
产品名称
Firocoxib, VETRANAL®, analytical standard
InChI
1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
SMILES string
O=S(C1=CC=C(C2=C(OCC3CC3)C(OC2(C)C)=O)C=C1)(C)=O
InChI key
FULAPETWGIGNMT-UHFFFAOYSA-N
grade
analytical standard
product line
VETRANAL®
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
Lauretta Maggi et al.
International journal of molecular sciences, 20(12) (2019-06-27)
An electrospinning process was optimized to produce fibers of micrometric size with different combinations of polymeric and surfactant materials to promote the dissolution rate of an insoluble drug: firocoxib. Scanning Electron Microscopy (SEM) showed that only some combinations of the
L Goodman et al.
Journal of veterinary internal medicine, 23(1), 56-62 (2009-01-30)
Little is known about the effect of dual cyclooxygenase (COX) and lipoxygenase inhibition on canine gastric mucosal healing. This study compares the effects of putative dual COX and 5-lipoxygenase inhibition with that of COX-2 selective inhibition on gastric mucosal lesion
Vanessa L Cook et al.
American journal of veterinary research, 70(8), 992-1000 (2009-08-04)
To determine whether treatment of horses with firocoxib affects recovery of ischemic-injured jejunum, while providing effective analgesia. 18 horses. Horses (n = 6 horses/group) received saline (0.9% NaCl) solution (1 mL/50 kg, IV), flunixin meglumine (1.1 mg/kg, IV, q 12
John P Punke et al.
American journal of veterinary research, 69(9), 1203-1209 (2008-09-04)
To evaluate the in vivo effects of firocoxib, meloxicam, and tepoxalin on prostaglandin (PG) and leukotriene production in duodenal mucosa and other target tissues in dogs with chronic osteoarthritis (OA). 8 dogs with chronic, unilateral OA of the stifle joint.
James A Orsini et al.
American journal of veterinary research, 73(5), 664-671 (2012-04-27)
To generate data on the effects of firocoxib administration to horses with osteoarthritis. Client-owned horses with signs of lameness and joint pain associated with osteoarthritis. Firocoxib was administered as an oral paste (0.1 mg/kg, q 24 h) for 14 days.
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