32442
双甲脒代谢物 BTS 27271
PESTANAL®, analytical standard
别名:
N-(2,4-二甲苯基)-N′-甲基甲咪, N-甲基-N′-2,4-二甲苯基甲脒
等级
analytical standard
产品线
PESTANAL®
应用
agriculture
environmental
SMILES字符串
CN\C=N\c1ccc(C)cc1C
InChI
1S/C10H14N2.ClH/c1-8-4-5-10(9(2)6-8)12-7-11-3;/h4-7H,1-3H3,(H,11,12);1H
InChI key
VXSNJXDZTGFDMB-UHFFFAOYSA-N
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法律信息
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Metabolic conversion of N'-(2,4-dimethylphenyl)-N-methylformamidine pesticide and the analysis of the metabolites.
Z Naikai et al.
Bulletin of environmental contamination and toxicology, 65(1), 22-27 (2000-06-30)
M A Pass et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 99(1-2), 169-172 (1991-01-01)
1. Amitraz was rapidly metabolised to BTS27271 after intravenous administration to sheep. 2. Amitraz and BTS27271 had significant H1-histamine antagonist activity on isolated guinea-pig ileum. BTS27271 was approximately 3.3 times as potent as amitraz. 3. Intravenous injection of amitraz and
E A Abu-Basha et al.
Metabolism: clinical and experimental, 48(11), 1461-1469 (1999-12-03)
The study purpose was to investigate the direct effect of amitraz, a formamidine insecticide/acaricide, and its active metabolite BTS 27271 on insulin and glucagon secretion from the perfused rat pancreas. Amitraz and BTS 27271 (0.01, 0.1, 1, and 10 micromol/L)
V C Ravikumar et al.
Toxicology, 27(1), 71-80 (1983-05-01)
The mammalian neuromuscular toxicity of N'-(2,4-xylyl)-N-methyl formamidine hydrochloride (U-40481A) was evaluated by programmed screening. The LD50 for mice, determined 48 h after single, subcutaneous (s.c.) injections, was 107 mg/kg body wt. Acute toxicity signs included abnormal gait, hindlimb hyperextension, transient
D H Shin et al.
Toxicology and applied pharmacology, 128(1), 45-49 (1994-09-01)
Isolated uterine strips were used to study the effects of amitraz and its metabolites on porcine myometrial contractility during the luteal phase of the estrous cycle. Amitraz and its active metabolite BTS27271 (10(-8)-10(-5) M) caused a dose-dependent increase in myometrial
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