33930
氟罗沙星
VETRANAL®, analytical standard
别名:
6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基-1-哌嗪基)-4-氧代-3-喹啉羧酸, 6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基哌嗪)-4-氧代-3-喹啉羧酸, AM-833, 多氟哌酸, 多氟沙星
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关于此项目
经验公式（希尔记法）:
C17H18F3N3O3
化学文摘社编号:
分子量:
369.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN(CCF)c3c2F)C(O)=O
InChI
1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
InChI key
XBJBPGROQZJDOJ-UHFFFAOYSA-N
General description
Fleroxacin is an antimicrobial drug, belonging to the class of fluoroquinolones (FQs), which shows broad-spectrum activity against a wide range of Gram-negative and Gram-positive organisms.
Application
Fleroxacin may be used as an analytical reference standard for the determination of the analyte in biological fluids using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
High-performance liquid chromatography for the determination of three new fluoroquinolones, fleroxacin, temafloxacin and A-64730, in biological fluids.
Koechlin C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 491, 379-387 (1989)
Determination of the new fluoroquinolone fleroxacin and its N-demethyl and N-oxide metabolites in plasma and urine by high-performance liquid chromatography with fluorescence detection.
Heizmann P, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 527, 91-101 (1990)
Mirjana Cvijovic et al.
European journal of mass spectrometry (Chichester, England), 18(3), 313-322 (2012-07-28)
Fluoroquinolones (FQLs) are synthetic antibacterial agents containing a 4-oxo-1,4-dihydroquinoline skeleton. When concomintantly administered with other drugs which may contain metal ions, particularly Al(3+) (antacids, phosphate binders, vaccines etc) they may form metal-drug complexes. Pharmacokinetic studies showed that aluminium-quinolone interactions lead
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 33930-100MG-R | 04061834039570 |