33930
氟罗沙星
VETRANAL®, analytical standard
别名:
6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基-1-哌嗪基)-4-氧代-3-喹啉羧酸, 6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基哌嗪)-4-氧代-3-喹啉羧酸, AM-833, 多氟哌酸, 多氟沙星
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关于此项目
经验公式（希尔记法）:
C17H18F3N3O3
化学文摘社编号:
分子量:
369.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
SMILES string
CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN(CCF)c3c2F)C(O)=O
InChI key
XBJBPGROQZJDOJ-UHFFFAOYSA-N
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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General description
Fleroxacin is an antimicrobial drug, belonging to the class of fluoroquinolones (FQs), which shows broad-spectrum activity against a wide range of Gram-negative and Gram-positive organisms.
Application
Fleroxacin may be used as an analytical reference standard for the determination of the analyte in biological fluids using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Determination of the new fluoroquinolone fleroxacin and its N-demethyl and N-oxide metabolites in plasma and urine by high-performance liquid chromatography with fluorescence detection.
Heizmann P, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 527, 91-101 (1990)
High-performance liquid chromatography for the determination of three new fluoroquinolones, fleroxacin, temafloxacin and A-64730, in biological fluids.
Koechlin C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 491, 379-387 (1989)
Yanqing Wang et al.
Talanta, 77(5), 1667-1674 (2009-01-23)
This paper describes the enhanced separation of lomefloxacin, sparfloxacin, fleroxacin, norfloxacin, ofloxacin, gatifloxacin and pazufloxacin by capillary zone electrophoresis (CZE) using silica nanoparticles (SiNPs) as running buffer additive. The impact of SiNPs concentration on the resolution and selectivity of separation
Rui-qin Feng et al.
Guang pu xue yu guang pu fen xi = Guang pu, 25(9), 1468-1470 (2005-12-29)
Based on the complex formed by Zn2+ which can strengthen the relative fluorescence intensity of fleroxacin evidently, a novel photochemical fluorescence method was developed. The effects of the acidity, the concentration ratio of Zn2+ to fleroxacin, and the time for
Yongxia Fan et al.
Electrophoresis, 28(22), 4101-4107 (2007-10-18)
A rapid CE coupled with potential gradient detection (PGD) for the separation and detection of four quinolones, namely, enoxacin, ofloxacin (OFL), fleroxacin, and pazufloxacin, was described. Separation was performed in a fused-silica capillary (75 microm x 8.5 cm) using a
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