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34202

非那雄胺

VETRANAL®, analytical standard

别名:

N-叔丁基-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺, MK-906, N-(2-甲基-2-丙基)-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺

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关于此项目

经验公式（希尔记法）:
C23H36N2O2
化学文摘社编号:
98319-26-7
分子量:
372.54
UNSPSC Code:
41116107
PubChem Substance ID:
329754889
MDL number:
MFCD00869737
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2

InChI

1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1

InChI key

DBEPLOCGEIEOCV-WSBQPABSSA-N

Gene Information

human ... SRD5A2(6716)

Application

Finasteride may be used as an analytical reference standard for the determination of the analyte in biological fluids and pharmaceutical formulations by high performance liquid chromatography (HPLC) method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

选择性 5α-还原酶抑制剂；抗雄激素。

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCD8558

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High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching.
Takano T and Hata S
Journal of Chromatography. B, Biomedical Sciences and Applications, 676(1), 141-146 (1996)
Harkamal Kaur Randhawa et al.
JAMA dermatology, 149(6), 732-735 (2013-04-05)
Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disease for which there is no universally effective treatment. Patients typically present at puberty with tender subcutaneous nodules that can progress to dermal abscess formation. Antiandrogens have been used in the treatment
Ian M Thompson et al.
The New England journal of medicine, 369(7), 603-610 (2013-08-16)
In the Prostate Cancer Prevention Trial (PCPT), finasteride significantly reduced the risk of prostate cancer but was associated with an increased risk of high-grade disease. With up to 18 years of follow-up, we analyzed rates of survival among all study
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全球贸易项目编号

货号GTIN
34202-100MG04061826754801