35762
Alternariol-9-methyl ether
analytical standard
别名:
3,7-Dihydroxy-9-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one, Alternariol monomethyl ether
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关于此项目
经验公式（希尔记法）:
C15H12O5
化学文摘社编号:
分子量:
272.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI key
LCSDQFNUYFTXMT-UHFFFAOYSA-N
SMILES string
COc1cc(O)c2C(=O)Oc3cc(O)cc(C)c3-c2c1
InChI
1S/C15H12O5/c1-7-3-8(16)4-12-13(7)10-5-9(19-2)6-11(17)14(10)15(18)20-12/h3-6,16-17H,1-2H3
grade
analytical standard
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
−20°C
Quality Level
General description
Alternariol-9-methyl ether (AME) is a mycotoxin produced by fungus Alternaria and a major plant pathogen found in a wide variety of fruits and cereals products.
Application
Alternariol-9-methyl ether (AME) may be used as an analytical reference standard for the determination of the analyte in food products by liquid chromatography tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Analysis Note
purity : ≥96.0% (HPLC)
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--毒素类产品
此项目有
Total synthesis of masked Alternaria mycotoxins?sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME).
Mikula H, et al.
Tetrahedron, 69(48), 10322-10330 (2013)
Markus Fehr et al.
Molecular nutrition & food research, 53(4), 441-451 (2008-08-30)
Alternariol (AOH), a mycotoxin formed by Alternaria alternata, has been reported to possess genotoxic properties. However, the underlying mechanism of action is unclear. Here, we tested the hypothesis that interactions with DNA-topoisomerases play a role in the DNA-damaging properties of
Fatma Bensassi et al.
Toxicology, 290(2-3), 230-240 (2011-10-18)
Alternariol monomethyl ether (AME) is a major mycotoxin produced by fungi of the genus Alternaria and a common contaminant of food products such as fruits and cereals worldwide. AME can cause serious health problems for animals as well as for
Quantitation of free and modified Alternaria mycotoxins in European food products by LC-MS/MS.
Puntscher H, et al.
Food Control, 2017(48), 10322-10330 (2019)
Rodrigo F Magnani et al.
Journal of agricultural and food chemistry, 55(13), 4980-4986 (2007-06-01)
A method was developed for the quantification of alternariol and alternariol monomethyl ether on tangerines with and without symptoms of Alternaria brown spot disease. The method employs solid-phase extraction for cleanup, followed by high-performance liquid chromatography coupled with tandem mass
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