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Merck
CN

37012

Beauvericin

VETRANAL®, analytical standard

别名:

cyclo(D-α-Hydroxyisovaleryl-L-N-methyl-Phe)3

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经验公式(希尔记法):
C45H57N3O9
化学文摘社编号:
分子量:
783.95
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI key

GYSCAQFHASJXRS-UHFFFAOYSA-N

SMILES string

CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(OC(=O)C(Cc3ccccc3)N(C)C(=O)C(OC(=O)C(Cc4ccccc4)N(C)C1=O)C(C)C)C(C)C

InChI

1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

Quality Level

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General description

Beauvericin is a mycotoxin mainly produced by several fungi belonging to Fusarium genus, generally occurring in agricultural commodities.

Application

Beauvericin may be used as analytical reference standard for the quantification of the analyte in cultures of Fusarium subglutinans, naturally contaminated maize, and biological samples using various chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Preparation Note

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Analysis Note

purity : ≥92.5% (HPLC)

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography--tandem mass spectrometry
Devreese M, et al.
Talanta, 106(2), 212-219 (2013)
Determination of the Fusarium mycotoxins, fusaproliferin and beauvericin by high-performance liquid chromatography-electrospray ionization mass spectrometry
Sewram V, et al.
Journal of Chromatography A, 858(2), 175-185 (1999)
Simultaneous determination of beauvericin, enniatins, and fusaproliferin by high performance liquid chromatography
Monti.MS, et al.
Journal of Agricultural and Food Chemistry, 48(8), 3317-3320 (2000)
M J Ruiz et al.
Toxicon : official journal of the International Society on Toxinology, 58(4), 315-326 (2011-08-09)
Beauvericin (BEA), deoxynivalenol (DON) and T-2 toxin (T-2) are important food-borne mycotoxins that have been implicated in human health. In this study, the acute toxicity of individual and combined mycotoxins (BEA, DON and T-2) were tested in immortalized hamster ovarian
Syed M Qadri et al.
Toxicology, 283(1), 24-31 (2011-02-08)
Beauvericin is a mycotoxin with antiviral, antibacterial, nematicidal, insecticidal, cytotoxic, and apoptotic activity. Similar to nucleated cells erythrocytes may undergo suicidal death or eryptosis, which is characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte surface. Eryptosis may be

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