37860
3,4-二羟基苯乙酸
purum, ≥98.0% (T)
别名:
DOPAC, 高原儿茶酸
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关于此项目
线性分子式:
(HO)2C6H3CH2CO2H
化学文摘社编号:
分子量:
168.15
EC Number:
203-024-1
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
2211017
grade
purum
assay
≥98.0% (T)
mp
127-130 °C (lit.), 128-132 °C
SMILES string
OC(=O)Cc1ccc(O)c(O)c1
InChI
1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChI key
CFFZDZCDUFSOFZ-UHFFFAOYSA-N
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
B Fornstedt et al.
Journal of neural transmission. Parkinson's disease and dementia section, 1(4), 279-295 (1989-01-01)
The concentrations of the 5-S-cysteinyl adducts of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and 3,4-dihydroxyphenylalanine (DOPA) and the levels of noradrenaline (NA), DA, DOPAC and DOPA were determined in the putamen (PUT), caudate nucleus (CN) and substantia nigra (SN) of human
Muhammed Saif et al.
Behavioural brain research, 243, 294-299 (2013-01-30)
Zebrafish are gaining popularity in behavioural brain research as this species combines practical simplicity with system complexity. The dopaminergic system has been thoroughly investigated using mammals. Dopamine plays important roles in motor function and reward. Zebrafish have dopamine receptors homologous
David S Goldstein et al.
Journal of neurochemistry, 126(5), 591-603 (2013-06-22)
Intra-neuronal metabolism of dopamine (DA) begins with production of 3,4-dihydroxyphenylacetaldehyde (DOPAL),which is toxic. According to the 'catecholaldehyde hypothesis', DOPAL destroys nigrostriatal DA terminals and contributes to the profound putamen DA deficiency that characterizes Parkinson’s disease (PD). We tested the feasibility
Arthur G Fitzmaurice et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(2), 636-641 (2012-12-26)
Parkinson disease (PD) is a neurodegenerative disorder particularly characterized by the loss of dopaminergic neurons in the substantia nigra. Pesticide exposure has been associated with PD occurrence, and we previously reported that the fungicide benomyl interferes with several cellular processes
David S Goldstein et al.
The Journal of pharmacology and experimental therapeutics, 305(3), 800-811 (2003-03-22)
Human plasma contains several catechols, including the catecholamines norepinephrine, epinephrine, and dopamine, their precursor, L-3,4-dihydroxyphenylalanine (L-DOPA), and their deaminated metabolites, dihydroxyphenylglycol, the main neuronal metabolite of norepinephrine, and dihydroxyphenylacetic acid, a deaminated metabolite of dopamine. Products of metabolism of catechols
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H2504-250MG | 04061832884851 |
| H2504-1G | 04061826683521 |
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