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Merck
CN

37906

美他环素 盐酸盐

VETRANAL®, analytical standard

别名:

盐酸甲烯土霉素

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关于此项目

经验公式(希尔记法):
C22H22N2O8 · HCl
化学文摘社编号:
分子量:
478.88
EC Number:
223-568-3
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
5470951
MDL number:
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InChI key

VZQARNDJLLWXGL-CCHMMTNSSA-N

InChI

1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1

SMILES string

Cl[H].[H][C@@]12[C@@H](O)[C@]3([H])C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

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General description

Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the solubility of Product 37906, Methacycline? 

    Product 37906, Methacycline, is soluble in water.  It is sparingly soluble in alcohol.  It is also practically insoluble in ether and chloroform.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

M Tod et al.
Journal of pharmacokinetics and biopharmaceutics, 22(2), 129-146 (1994-04-01)
Use of optimal sampling theory (OST) in pharmacokinetic studies allows the number of sampling times to be greatly reduced without loss in parameter estimation precision. OST has been applied to the determination of the bioavailability parameters (area under the curve
Thao Do Thi et al.
Electrophoresis, 27(12), 2317-2329 (2006-05-24)
A CE method for metacycline (MTC) determination was investigated in an inter-laboratory experiment. Many problems were encountered in this study, most of which were related to the transfer of the method to different CE equipment. The reported problems could be
Xian Xiang Sun et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 23(2), 231-233 (2007-02-14)
An internal solid contact sensor (ISCS) for the determination of methacycline hydrochloride (MC.Cl), Pt/PPy/PVC(MC-PT), is described, based on the use of conducting poly(pyrrole) (PPy) as solid contact material and MC-phosphotungstate (PT) as the ion exchanger and dibutyl phthalate (DBP) as
E C Gil et al.
Electrophoresis, 22(3), 497-502 (2001-03-22)
The development and validation of an optimized capillary electrophoresis method for the determination of metacycline in the presence of its related substances by capillary electrophoresis is shown. The influence of methanol as organic modifier, buffer pH, buffer concentration, capillary length
Na Zhang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(5), 541-544 (2005-05-26)
A new spectrofluorometric method is described for the determination of metacycline (MC), based on modified enzyme-amplified lanthanide luminescence. Under the optimum conditions, Eu3+-MC forms a ternary complex with lysozyme in close proximity. Then lysozyme can remarkably enhance the characteristic fluorescence

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