38171
6-巯基嘌呤
analytical standard
别名:
6-嘌呤硫醇, 6-硫代嘌呤
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C5H4N4S
化学文摘社编号:
分子量:
152.18
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
200-037-4
MDL number:
InChI key
GLVAUDGFNGKCSF-UHFFFAOYSA-N
InChI
1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
SMILES string
S=C1NC=NC2=C1NC=N2
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
storage condition
under inert gas (argon)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤20% water
application(s)
pharmaceutical
format
neat
Quality Level
Gene Information
human ... PPAT(5471)
General description
6-巯基嘌呤（6-MP）为嘌呤类似物，常用于治疗儿童急性淋巴细胞白血病。也广泛用于治疗皮质类固醇依赖性炎症性肠病（IBD）或克罗恩氏病（Crohn′s disease）。
Application
6-巯基嘌呤（6-MP）可作为分析参考标准品，通过高效液相色谱法（HPLC）技术测定生物样品 中的分析物。
Other Notes
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Muta. 2 - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity.
Cuffari C, et al.
Gut, 39(3), 401-406 (1996)
Development and validation of an HPLC method for the rapid and simultaneous determination of 6-mercaptopurine and four of its metabolites in plasma and red blood cells
Hawwa AF, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(2), 401-409 (2009)
Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia.
Lennard L, et al.
British Journal of Clinical Pharmacology, 16(4), 359-363 (1983)
Determination of 6-mercaptopurine and azathioprine in plasma by high-performance liquid chromatography
Ding TL and Benet LZ
Journal of Chromatography. B, Biomedical Sciences and Applications, 163(3), 281-288 (1979)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持