39145
N-(7-二甲氨基-4-甲基-3-香豆素基)马来酰亚胺
≥99.0% (HPLC)
别名:
DACM-3
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关于此项目
经验公式（希尔记法）:
C16H14N2O4
化学文摘社编号:
分子量:
298.29
EC Number:
259-499-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1545346
MDL number:
assay
≥99.0% (HPLC)
mp
218-220 °C (lit.)
fluorescence
λex 398 nm; λem 482 nm in 0.1 M phosphate pH 7.0 (after derivatization with 2-mercaptoethanol)
suitability
suitable for fluorescence
SMILES string
CN(C)c1ccc2C(C)=C(N3C(=O)C=CC3=O)C(=O)Oc2c1
InChI
1S/C16H14N2O4/c1-9-11-5-4-10(17(2)3)8-12(11)22-16(21)15(9)18-13(19)6-7-14(18)20/h4-8H,1-3H3
InChI key
ADEORFBTPGKHRP-UHFFFAOYSA-N
Other Notes
Fluorescent reagent with high selectivity for protein thiols and with superior fluorescence and water solubility properties than dansyl chloride
法规信息
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Y. Kanaoka
Angewandte Chemie (International Edition in English), 89, 141-141 (1977)
T Ohyashiki et al.
Journal of biochemistry, 115(2), 224-229 (1994-02-01)
The effects of lipid peroxidation on the SH reactivity of the proteins in porcine intestinal brush-border membranes were examined using a fluorogenic thiol reagent, N-[7-dimethyl-amino-4-methylcoumarinyl]maleimide (DACM) in relation to lipid organization. Changes in the lipid organization were assessed by measurement
L A Jurado et al.
Biochimica et biophysica acta, 1292(1), 188-196 (1996-01-04)
We studied the transition metal ion requirements for activity and sulfhydryl group reactivity in phospho enol pyruvate carboxykinase (PEP-carboxykinase; ATP:oxaloacetate carboxylase (transphosphorylating), EC 4.1.1.49), a key enzyme in the energy metabolism of the protozan parasite Trypanosoma (Schizotrypanum) cruzi. As for