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Merck
CN

41866

Supelco

(S)-(+)-7,8-Dihydrokavain

analytical standard

别名:

(6S)-5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one, 7,8-Dihydrokawain, Dihydrokavain, Marindinin

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关于此项目

经验公式(希尔记法):
C14H16O3
化学文摘社编号:
分子量:
232.28
Beilstein:
15362
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥98.0% (HPLC)

旋光性

[α]/D 29±2°, c = 0.5 in methanol

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤5.0% water

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

COC1=CC(=O)O[C@@H](CCc2ccccc2)C1

InChI

1S/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6,10,12H,7-9H2,1H3/t12-/m0/s1

InChI key

VOOYTQRREPYRIW-LBPRGKRZSA-N

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应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K K Smith et al.
Psychopharmacology, 155(1), 86-90 (2001-05-26)
Piper methysticum extract (kava kava) possesses numerous therapeutic properties, but it is unknown which of its principle constituents (kavalactones) subserve such effects. This experiment sought to characterize the putative anxiolytic properties of P. methysticum extract and its six principle kavalactones
J Friese et al.
Planta medica, 64(5), 458-459 (1998-08-05)
The mode of action of the kava pyrones, kavain, dihydrokavain and dihydromethysticin on the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to epitope 2 of voltage-dependent Na+ channels was investigated by performing saturation experiments in the presence and absence of these kava
Karen Savage et al.
Phytotherapy research : PTR, 32(1), 3-18 (2017-11-24)
Anxiety disorders are chronic and functionally disabling conditions with high psychological stress, characterised by cognitive symptoms of excessive worry and focus difficulties and physiological symptoms such as muscle tension and insomnia. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter within the
Lili Lin et al.
Organic letters, 10(6), 1311-1314 (2008-02-29)
An efficient catalytic asymmetric hetero-Diels-Alder reaction of Brassard's diene with aliphatic aldehydes was reported. The catalyst, which was generated from (R)-BINOL, Ti(i-PrO)4, and 4-picolyl chloride hydrochloride, promoted the reaction smoothly to afford the corresponding alpha,beta-unsaturated delta-lactone derivatives in moderate-to-good yields
Matthias Unger et al.
Planta medica, 68(12), 1055-1058 (2002-12-21)
Inhibitors of cytochrome P450 3A4 (CYP3A4) were identified in crude extracts from the rhizomes of Piper methysticum G. Forst. (Kava-Kava) using bioassay-guided fractionation. After preliminary purification of an ethyl acetate extract with solid phase extraction, the eluate was further fractionated

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