41866
(S)-(+)-7,8-Dihydrokavain
analytical standard
别名:
(6S)-5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one, 7,8-Dihydrokawain, Dihydrokavain, Marindinin
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关于此项目
经验公式（希尔记法）:
C14H16O3
化学文摘社编号:
分子量:
232.28
Beilstein:
15362
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥98.0% (HPLC)
旋光性
[α]/D 29±2°, c = 0.5 in methanol
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤5.0% water
应用
food and beverages
包装形式
neat
储存温度
2-8°C
SMILES字符串
COC1=CC(=O)O[C@@H](CCc2ccccc2)C1
InChI
1S/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6,10,12H,7-9H2,1H3/t12-/m0/s1
InChI key
VOOYTQRREPYRIW-LBPRGKRZSA-N
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Karen Savage et al.
Phytotherapy research : PTR, 32(1), 3-18 (2017-11-24)
Anxiety disorders are chronic and functionally disabling conditions with high psychological stress, characterised by cognitive symptoms of excessive worry and focus difficulties and physiological symptoms such as muscle tension and insomnia. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter within the
J Friese et al.
Planta medica, 64(5), 458-459 (1998-08-05)
The mode of action of the kava pyrones, kavain, dihydrokavain and dihydromethysticin on the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to epitope 2 of voltage-dependent Na+ channels was investigated by performing saturation experiments in the presence and absence of these kava
K K Smith et al.
Psychopharmacology, 155(1), 86-90 (2001-05-26)
Piper methysticum extract (kava kava) possesses numerous therapeutic properties, but it is unknown which of its principle constituents (kavalactones) subserve such effects. This experiment sought to characterize the putative anxiolytic properties of P. methysticum extract and its six principle kavalactones
Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro.
Johanna Weiss et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(11), 1580-1583 (2005-07-30)
Root extracts from kava-kava (Piper methysticum G. Forst) are clinically used for the treatment of anxiety and restlessness. Due to reported cases of liver toxicity, kava-kava extracts were withdrawn from the market in several countries in 2002. Because the efflux
Michael P Pollastri et al.
Chemical biology & drug design, 74(2), 121-128 (2009-06-23)
There is a substantial unmet need for new classes of drugs that block TNF-alpha-mediated inflammation, and particularly for small molecule agents that can be taken orally. We have screened a library of natural products against an assay measuring TNF-alpha secretion
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