424455
Resorufin
Dye content 95 %
别名:
7-羟基-3H-吩恶嗪-3-酮, NSC 12097
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关于此项目
经验公式（希尔记法）:
C12H7NO3
化学文摘社编号:
分子量:
213.19
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
211-241-8
Beilstein/REAXYS Number:
174850
MDL number:
产品名称
Resorufin, Dye content 95 %
InChI key
HSSLDCABUXLXKM-UHFFFAOYSA-N
InChI
1S/C12H7NO3/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9/h1-6,14H
SMILES string
O=C(C=C1)C=C2C1=NC3=CC=C(O)C=C3O2
form
powder
composition
Dye content, 95%
mp
>300 °C (lit.)
λmax
573 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
试卤灵已被用于测量过氧化氢的产生。
General description
试卤灵，一种可用于直接观察细胞呼吸的氧化还原探针。它具有高荧光性，最大激发波长为563nm，最大发射波长为587nm。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Hubert M Piwonski et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(22), E1437-E1443 (2012-05-09)
Enzymatic inhibition by product molecules is an important and widespread phenomenon. We describe an approach to study product inhibition at the single-molecule level. Individual HRP molecules are trapped within surface-tethered lipid vesicles, and their reaction with a fluorogenic substrate is
Yutaka Hitomi et al.
Analytical chemistry, 83(24), 9213-9216 (2011-11-18)
We developed a metal-based fluorescent probe for H(2)O(2) called MBFh1, which has an iron complex as a reaction site for H(2)O(2) and a 3,7-dihydroxyphenoxazine derivative as the fluorescent reporter unit. The iron complex reacts quickly with H(2)O(2) to form oxidants
Eduardo Vottero et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 16(6), 899-912 (2011-05-14)
CYP102A1, originating from Bacillus megaterium, is a highly active enzyme which has attracted much attention because of its potential applicability as a biocatalyst for oxidative reactions. Previously we developed drug-metabolizing mutant CYP102A1 M11 by a combination of site-directed and random
Malena B Rone et al.
Molecular endocrinology (Baltimore, Md.), 26(11), 1868-1882 (2012-09-14)
Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs
Julian G Jude et al.
Oncogene, 34(10), 1253-1262 (2014-04-01)
Given the importance of deregulated phosphoinositide (PI) signaling in leukemic hematopoiesis, genes coding for proteins that regulate PI metabolism may have significant and as yet unappreciated roles in leukemia. We performed a targeted knockdown (KD) screen of PI modulator genes
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